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NCT06299436 · ClinicalTrials.gov registry record

Hemodynamic Assessment of underLying myocyTe Function in Right Heart Failure

A clinical trial of Pulmonary Hypertension and Heart Failure With Reduced Ejection Fraction, sponsored by Johns Hopkins University.

Recruiting
Registry status
50
Enrollment target
1
Study location

NCT06299436 is a study of Pulmonary Hypertension and Heart Failure With Reduced Ejection Fraction that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 50 participants, below the 613-participant average among 72 other Pulmonary Hypertension trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06299436, a study of Pulmonary Hypertension and Heart Failure With Reduced Ejection Fraction, is actively recruiting participants, sponsored by Johns Hopkins University.

RECRUITING
Registry status
50 participants
Enrollment target
1
Study location

Study Summary

Right ventricular (RV) failure is recognized to worsen patient outcomes in the setting of heart failure with reduced ejection fraction (HFrEF)-related pulmonary hypertension (PH), yet the investigators fall short in trying to identify and treat it. The current proposal will (1) determine the best clinical indicators of intrinsic RV myocyte contractile failure in humans with HFrEF-PH, (2) clarify underlying mechanisms, and (3) test novel treatments on RV myocytes. The long-term goal of this proposal will be to better identify and treat RV failure in humans suffering from HFrEF-PH.

Conditions Studied

Pulmonary Hypertension Heart Failure With Reduced Ejection Fraction Right Heart Failure Due to Left Heart Failure

Study Locations (1)

Maryland

  • Johns Hopkins Hospital - Baltimore

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2024-12-10
Est. Completion 2029-03-31

Sponsor

Johns Hopkins University

1,448 total trials

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What the Registry Record Tells You About NCT06299436

The ClinicalTrials.gov registry entry for NCT06299436 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 613-participant average among 72 other Pulmonary Hypertension trials with a reported enrollment target (92% lower). The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Pulmonary Hypertension appearing as the primary indexed condition, and to 0 interventions.

NCT06299436 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT06299436 about?

NCT06299436 is a clinical study titled "Hemodynamic Assessment of underLying myocyTe Function in Right Heart Failure". Right ventricular (RV) failure is recognized to worsen patient outcomes in the setting of heart failure with reduced ejection fraction (HFrEF)-related pulmonary hypertension (PH), yet the investigators fall short in trying to identify and treat it. The current proposal will (1) determine the best cl...

What is the current status of trial NCT06299436?

This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2024-12-10. Estimated completion is 2029-03-31.

What conditions does trial NCT06299436 study?

This clinical trial studies the following conditions: Pulmonary Hypertension, Heart Failure With Reduced Ejection Fraction, Right Heart Failure Due to Left Heart Failure.

Who is sponsoring clinical trial NCT06299436?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06299436 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.