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NCT07115043 · ClinicalTrials.gov registry record · Phase 1
A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors
A Phase 1 study of Non-Small Cell Lung Cancer and Melanoma, sponsored by AstraZeneca.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 60
- Enrollment target
- 11
- Study locations
NCT07115043: Recruiting Phase 1 study of Non-Small Cell Lung Cancer and Melanoma, sponsored by AstraZeneca.
NCT07115043 is a Phase 1 study of Non-Small Cell Lung Cancer and Melanoma that is actively recruiting participants, run by AstraZeneca. The registered enrollment target is 60 participants, below the 652-participant average among 454 other Non-Small Cell Lung Cancer trials with a reported enrollment target (91% lower). The trial reports 11 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07115043, a Phase 1 study of Non-Small Cell Lung Cancer and Melanoma, is actively recruiting participants, sponsored by AstraZeneca.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 60 participants
- Enrollment target
- 11
- Study locations
Study Summary
A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors
Primary Outcome
To assess the safety and tolerability, characterize the DLTs, and determine the MTD and RP2D(s) of AZD6750 as a single agent and in combination with other anti-cancer agents as specified in each respective module
Conditions Studied
Interventions
- DRUG AZD6750
- DRUG rilvegostomig
Study Locations (11)
Other
- Research Site - East Melbourne
- Research Site - Chūōku
- Research Site - Kashiwa
- Research Site - Seoul
- Research Site - Seoul
Texas
- Research Site - Houston
- Research Site - San Antonio
Michigan
- Research Site - Grand Rapids
Missouri
- Research Site - St Louis
Pennsylvania
- Research Site - Pittsburgh
Virginia
- Research Site - Fairfax
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-07-29 |
| Est. Completion | 2029-10-02 |
| Phase | Phase 1 |
What NCT07115043 shows while recruiting
NCT07115043 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 652-participant average among 454 other Non-Small Cell Lung Cancer trials with a reported enrollment target (91% lower).
The record links to 9 conditions, with Non-Small Cell Lung Cancer appearing as the primary indexed condition, and to 2 interventions - of which AZD6750 is the first listed.
NCT07115043 lists 11 locations in 6 states (Other, Texas, Michigan).
Frequently Asked Questions
What is clinical trial NCT07115043 about?
NCT07115043 is a clinical study titled "A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors". A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors
What is the current status of trial NCT07115043?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2025-07-29. Estimated completion is 2029-10-02.
What conditions does trial NCT07115043 study?
This clinical trial studies the following conditions: Non-Small Cell Lung Cancer, Melanoma, Head and Neck Squamous Cell Carcinoma, Renal Cell Carcinoma, Triple Negative Breast Cancer.
What interventions are being tested in trial NCT07115043?
The interventions under investigation include: AZD6750 (DRUG), rilvegostomig (DRUG).
Who is sponsoring clinical trial NCT07115043?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07115043 being conducted?
This trial has 11 study locations across Michigan, Missouri, Pennsylvania, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Non-Small Cell Lung Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07115043's enrollment target sits among peer trials
60 313th of 454 higher than 135 of 454 other Non-Small Cell Lung Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Non-Small Cell Lung Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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