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NCT07099222 · ClinicalTrials.gov registry record · Phase 1
Efficacy of Non-weight Based, Low Dose Dex-Dex Adjuncts in Prolonging Peripheral Nerve Blocks
A Phase 1 study of Postoperative Pain and Constipation, sponsored by University of Arizona.
- Active
- Registry status
- Phase 1
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT07099222: Active Phase 1 study of Postoperative Pain and Constipation, sponsored by University of Arizona.
NCT07099222 is a Phase 1 study of Postoperative Pain and Constipation that is active but no longer recruiting, run by University of Arizona. The registered enrollment target is 100 participants, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (57% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07099222, a Phase 1 study of Postoperative Pain and Constipation, is active but no longer recruiting, sponsored by University of Arizona.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical study is to improve upon the standard practice of utilizing nerve blocks to enhance the satisfaction of patients undergoing shoulder, or foot and ankle surgery regarding their quality of pain control, the duration of their nerve blocks, as well as the avoidance of opioid medications and subsequently their undesirable side effects. The researchers hypothesize that dexmedetomidine and dexamethasone (Dex-Dex) will work synergistically as adjuncts in a low, non-weight based formula. This would allow the investigators to improve patient satisfaction by providing them with a superior means of pain control that is longer in duration with a decreased probability of unwanted side effects. The proposed clinical study will be a prospective, randomized control trial.
Primary Outcome
Using automated daily emailed patient surveys to assess for the duration of the peripheral nerve block.
Conditions Studied
Interventions
- DRUG Low, non-weight based dose of Dexamethasone and Dexmedetomidine in peripheral nerve blocks
- DRUG Ropivacaine with low, non weight based Dexamethasone additive
Study Locations (1)
Arizona
- Banner - University Medical Center South - Tucson
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2024-10-10 |
| Est. Completion | 2026-12-31 |
| Phase | Phase 1 |
What the registry record for NCT07099222 still lists
NCT07099222 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (57% lower).
The record links to 7 conditions, with Postoperative Pain appearing as the primary indexed condition, and to 2 interventions - of which Low, non-weight based dose of Dexamethasone and Dexmedetomidine in peripheral nerve blocks is the first listed.
NCT07099222 reports a single indexed study location in Arizona.
Frequently Asked Questions
What is clinical trial NCT07099222 about?
NCT07099222 is a clinical study titled "Efficacy of Non-weight Based, Low Dose Dex-Dex Adjuncts in Prolonging Peripheral Nerve Blocks". The goal of this clinical study is to improve upon the standard practice of utilizing nerve blocks to enhance the satisfaction of patients undergoing shoulder, or foot and ankle surgery regarding their quality of pain control, the duration of their nerve blocks, as well as the avoidance of opioid me...
What is the current status of trial NCT07099222?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 100 participants. The study started on 2024-10-10. Estimated completion is 2026-12-31.
What conditions does trial NCT07099222 study?
This clinical trial studies the following conditions: Postoperative Pain, Constipation, Dizziness, Nausea and Vomiting, Postoperative, Pain After Surgery.
What interventions are being tested in trial NCT07099222?
The interventions under investigation include: Low, non-weight based dose of Dexamethasone and Dexmedetomidine in peripheral nerve blocks (DRUG), Ropivacaine with low, non weight based Dexamethasone additive (DRUG).
Who is sponsoring clinical trial NCT07099222?
This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07099222 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07099222's enrollment target sits among peer trials
100 55th of 120 higher than 59 of 120 other Postoperative Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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