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NCT07093554 · ClinicalTrials.gov registry record · Phase 1

Cilta-Talq Fusion Study: A Phase 1b Study of Talquetamab Bridging Therapy Followed by Ciltacabtagene Autoleucel in Patients With Relapsed/Refractory Multiple Myeloma

A Phase 1 study of Refractory Multiple Myeloma and Relapse Multiple Myeloma, sponsored by Medical College of Wisconsin.

Recruiting
Registry status
Phase 1
Development phase
31
Enrollment target
1
Study location

NCT07093554 is a Phase 1 study of Refractory Multiple Myeloma and Relapse Multiple Myeloma that is actively recruiting participants, run by Medical College of Wisconsin. The registered enrollment target is 31 participants, below the 48-participant average among 67 other Refractory Multiple Myeloma trials with a reported enrollment target (35% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07093554, a Phase 1 study of Refractory Multiple Myeloma and Relapse Multiple Myeloma, is actively recruiting participants, sponsored by Medical College of Wisconsin.

RECRUITING
Registry status
Phase 1
Development phase
31 participants
Enrollment target
1
Study location

Study Summary

This is a single-arm, open-label, phase 1b study evaluating the safety and feasibility of using talquetamab as bridging therapy prior to cilta-cel in patients with relapsed and refractory multiple myeloma (RRMM).

Interventions

  • DRUG Talquetamab
  • DRUG Ciltacabtagene Autoleucel

Study Locations (1)

Wisconsin

  • Froedtert & the Medical College of Wisconsin - Milwaukee

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2025-12-02
Est. Completion 2028-01-01
Phase Phase 1

Sponsor

Medical College of Wisconsin

447 total trials

What the Registry Record Tells You About NCT07093554

The ClinicalTrials.gov registry entry for NCT07093554 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 31 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 48-participant average among 67 other Refractory Multiple Myeloma trials with a reported enrollment target (35% lower). The listed sponsor is Medical College of Wisconsin, which has 447 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Refractory Multiple Myeloma appearing as the primary indexed condition, and to 2 interventions - of which Talquetamab is the first listed.

NCT07093554 reports 1 study location spanning 1 distinct geographic area - top geographies include Wisconsin.

Frequently Asked Questions

What is clinical trial NCT07093554 about?

NCT07093554 is a clinical study titled "Cilta-Talq Fusion Study: A Phase 1b Study of Talquetamab Bridging Therapy Followed by Ciltacabtagene Autoleucel in Patients With Relapsed/Refractory Multiple Myeloma". This is a single-arm, open-label, phase 1b study evaluating the safety and feasibility of using talquetamab as bridging therapy prior to cilta-cel in patients with relapsed and refractory multiple myeloma (RRMM).

What is the current status of trial NCT07093554?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 31 participants. The study started on 2025-12-02. Estimated completion is 2028-01-01.

What conditions does trial NCT07093554 study?

This clinical trial studies the following conditions: Refractory Multiple Myeloma, Relapse Multiple Myeloma.

What interventions are being tested in trial NCT07093554?

The interventions under investigation include: Talquetamab (DRUG), Ciltacabtagene Autoleucel (DRUG).

Who is sponsoring clinical trial NCT07093554?

This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07093554 being conducted?

This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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