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NCT07086014 · ClinicalTrials.gov registry record

Methamphetamine Cue-reactivity

A clinical trial of Methamphetamine Use Disorder, sponsored by Icahn School of Medicine at Mount Sinai.

Recruiting
Registry status
88
Enrollment target
1
Study location

NCT07086014: Recruiting study of Methamphetamine Use Disorder, sponsored by Icahn School of Medicine at Mount Sinai.

NCT07086014 is a study of Methamphetamine Use Disorder that is actively recruiting participants, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 88 participants, above the 48-participant average among 12 other Methamphetamine Use Disorder trials with a reported enrollment target (83% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07086014, a study of Methamphetamine Use Disorder, is actively recruiting participants, sponsored by Icahn School of Medicine at Mount Sinai.

RECRUITING
Registry status
88 participants
Enrollment target
1
Study location

Study Summary

In this observational cohort study, the researchers propose to first identify a psychophysiological marker of methamphetamine cue-reactivity and its incubation with abstinence from methamphetamine use (MUD) and examine group-differences between men who have sex with men (MSM) and non-MSM MUD. The primary objective is to identify psychophysiological markers of methamphetamine (MA) cue-reactivity and its abstinence incubation. The secondary objective is to examine group-differences in methamphetamine use disorder (MUD) individuals between homosexual men (MSM) and heterosexual men (non-MSM). The primary endpoint is to assess incubation of cue-reactivity longitudinally with its reduction in cognitive reappraisal, and the secondary endpoint is to examine the impact of cognitive reappraisal on clinical outcomes of methamphetamine use disorder (MUD) in homosexual men (MSM). 2-year long study. Screening and enrollment will be done at different locations of the Addiction Institute of Mount Sinai. The EEG session will be done at Icahn School of Medicine at Mount Sinai. Participation in the research study will be for a single EEG session.

Primary Outcome

Change in amplitude (or incubation of) the EEG-derived late positive potential (LPP) - an objective neurophysiological marker of drug cue-reactivity - occurs 400 msec after the onset of a drug-related cue. The LPP amplitude has also shown to predict self-reported craving, simulated drug-seeking behavior and relapse, highlighting the clinical utility of this objective metric of cue-reactivity.

Conditions Studied

Methamphetamine Use Disorder

Interventions

  • BEHAVIORAL Cognitive Reappraisal

Study Locations (1)

New York

  • Icahn School of Medicine at Mount Sinai - New York

Trial Details

FieldValue
Enrollment Target 88 participants
Start Date 2024-08-19
Est. Completion 2025-08-30
Icahn School of Medicine at Mount Sinai

708 total trials

What NCT07086014 shows while recruiting

NCT07086014 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 88 participants, a relatively small participant target, above the 48-participant average among 12 other Methamphetamine Use Disorder trials with a reported enrollment target (83% higher).

The record links to 1 condition, with Methamphetamine Use Disorder appearing as the primary indexed condition, and to 1 intervention - of which Cognitive Reappraisal is the first listed.

NCT07086014 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT07086014 about?

NCT07086014 is a clinical study titled "Methamphetamine Cue-reactivity". In this observational cohort study, the researchers propose to first identify a psychophysiological marker of methamphetamine cue-reactivity and its incubation with abstinence from methamphetamine use (MUD) and examine group-differences between men who have sex with men (MSM) and non-MSM MUD. The p...

What is the current status of trial NCT07086014?

This trial is currently recruiting. The enrollment target is 88 participants. The study started on 2024-08-19. Estimated completion is 2025-08-30.

What conditions does trial NCT07086014 study?

This clinical trial studies the following conditions: Methamphetamine Use Disorder.

What interventions are being tested in trial NCT07086014?

The interventions under investigation include: Cognitive Reappraisal (BEHAVIORAL).

Who is sponsoring clinical trial NCT07086014?

This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07086014 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Methamphetamine Use Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07086014's enrollment target sits among peer trials

88 2nd of 12 the highest of 12 other Methamphetamine Use Disorder trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Methamphetamine Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT07086014

Source: ClinicalTrials.gov NCT07086014, the US trial registry maintained by the National Library of Medicine. NCT07086014 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.