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RECRUITING Phase 1

A Clinical Trial to Evaluate EDV Nanocell Therapy With Gemcitabine and Nab-paclitaxel in Pancreatic Cancer

NCT07049055 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to evaluate the safety and tolerability and overall survival (OS) of E-EDV-D682/GC in combination with gemcitabine and nab-paclitaxel versus gemcitabine and nab-paclitaxel alone in participants with metastatic pancreatic ductal adenocarcinoma (PDAC) who have progressed on therapy.

Interventions

  • DRUG Gemcitabine
  • DRUG E-EDV-D682
  • DRUG EDV-GC
  • DRUG Nab paclitaxel.

Study Locations (4)

California

  • Chan Soon-Shiong Institute for Medicine — El Segundo

New Jersey

  • Atlantic Health — Summit

New York

  • Columbia University Irving Medical Center — New York

Ohio

  • Taylor Cancer Center — Maumee

Trial Details

FieldValue
Enrollment Target 144 participants
Start Date 2026-01-12
Est. Completion 2028-09
Phase Phase 1

Sponsor

Engeneic Pty Limited

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07049055

The ClinicalTrials.gov registry entry for NCT07049055 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 144 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Engeneic Pty Limited, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with PDAC - Pancreatic Ductal Adenocarcinoma appearing as the primary indexed condition, and to 4 interventions — of which Gemcitabine is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07049055 reports 4 study locations spanning 4 distinct geographic areas — top geographies include California, New Jersey, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07049055 about?

NCT07049055 is a clinical study titled "A Clinical Trial to Evaluate EDV Nanocell Therapy With Gemcitabine and Nab-paclitaxel in Pancreatic Cancer". The purpose of this study is to evaluate the safety and tolerability and overall survival (OS) of E-EDV-D682/GC in combination with gemcitabine and nab-paclitaxel versus gemcitabine and nab-paclitaxel alone in participants with metastatic pancreatic ductal adenocarcinoma (PDAC) who have progressed o...

What is the current status of trial NCT07049055?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 144 participants. The study started on 2026-01-12. Estimated completion is 2028-09.

What conditions does trial NCT07049055 study?

This clinical trial studies the following conditions: PDAC - Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer, Metastatic. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07049055?

The interventions under investigation include: Gemcitabine (DRUG), E-EDV-D682 (DRUG), EDV-GC (DRUG), Nab paclitaxel. (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07049055?

This trial is sponsored by Engeneic Pty Limited, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07049055 being conducted?

This trial has 4 study locations across California, New Jersey, New York, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial