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NCT07011654 · ClinicalTrials.gov registry record · Phase 1

Study of Naxitamab and Sacituzumab Govitecan in Patients With Metastatic Triple-negative Breast Cancer (TNBC)

A Phase 1 study of Metastatic Triple-Negative Breast Cancer, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 1
Development phase
31
Enrollment target
1
Study location

NCT07011654 is a Phase 1 study of Metastatic Triple-Negative Breast Cancer that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 31 participants, below the 86-participant average among 5 other Metastatic Triple-Negative Breast Cancer trials with a reported enrollment target (64% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07011654, a Phase 1 study of Metastatic Triple-Negative Breast Cancer, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 1
Development phase
31 participants
Enrollment target
1
Study location

Study Summary

This phase I/II trial tests the safety, best dose, and effectiveness of naxitamab in combination with sacituzumab govitecan in treating patients with triple-negative breast cancer (TNBC) that has spread from where it first started (primary site) to other places in the body (metastatic).

Interventions

  • DRUG Sacituzumab govitecan
  • DRUG Naxitamab

Study Locations (1)

Texas

  • The University of Texas M. D. Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2025-09-19
Est. Completion 2030-07-01
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT07011654

The ClinicalTrials.gov registry entry for NCT07011654 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 31 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 86-participant average among 5 other Metastatic Triple-Negative Breast Cancer trials with a reported enrollment target (64% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Metastatic Triple-Negative Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Sacituzumab govitecan is the first listed.

NCT07011654 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT07011654 about?

NCT07011654 is a clinical study titled "Study of Naxitamab and Sacituzumab Govitecan in Patients With Metastatic Triple-negative Breast Cancer (TNBC)". This phase I/II trial tests the safety, best dose, and effectiveness of naxitamab in combination with sacituzumab govitecan in treating patients with triple-negative breast cancer (TNBC) that has spread from where it first started (primary site) to other places in the body (metastatic).

What is the current status of trial NCT07011654?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 31 participants. The study started on 2025-09-19. Estimated completion is 2030-07-01.

What conditions does trial NCT07011654 study?

This clinical trial studies the following conditions: Metastatic Triple-Negative Breast Cancer.

What interventions are being tested in trial NCT07011654?

The interventions under investigation include: Sacituzumab govitecan (DRUG), Naxitamab (DRUG).

Who is sponsoring clinical trial NCT07011654?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07011654 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.