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NCT05570253 · ClinicalTrials.gov registry record · Phase 2
A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer
A Phase 2 study of Breast Cancer and Metastatic Triple-Negative Breast Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 55
- Enrollment target
- 10
- Study locations
NCT05570253: Recruiting Phase 2 study of Breast Cancer and Metastatic Triple-Negative Breast Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
NCT05570253 is a Phase 2 study of Breast Cancer and Metastatic Triple-Negative Breast Cancer that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 55 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower). The trial reports 10 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05570253, a Phase 2 study of Breast Cancer and Metastatic Triple-Negative Breast Cancer, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 55 participants
- Enrollment target
- 10
- Study locations
Study Summary
The researchers are doing this study to find out whether the study drug, SDX-7320, when combined with the standard chemotherapy eribulin, is an effective treatment for people with TNBC and metabolic dysfunction. The researchers will also look at whether the study treatment (SDX-7320 combined with eribulin) is safe and causes few or mild side effects in participants. The researchers will compare this treatment approach to eribulin alone.
Primary Outcome
The Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) is a validated tool for the assessment of insulin resistance.87 HOMA-IR is calculated as follows: fasting serum insulin (μU/mL) × fasting plasma glucose (mmol L -1 )/22.5).
Conditions Studied
Interventions
- OTHER Placebo
- DRUG Eribulin
- DRUG SDX-7320
Study Locations (10)
New Jersey
- Memorial Sloan Kettering Basking Ridge (All Protocol Activities) - Basking Ridge
- Hackensack Meridian Health - Hackensack
- Memorial Sloan Kettering Monmouth (All Protocol Activities) - Middletown
- Memorial Sloan Kettering Bergen (All Protocol Activities) - Montvale
New York
- Memorial Sloan Kettering Suffolk - Commack (All Protocol Activities) - Commack
- Memorial Sloan Kettering Westchester (All Protocol Activities) - Harrison
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) - New York
- Memorial Sloan Kettering Nassau (All Protocol Activities) - Uniondale
Florida
- BAPTIST ALLIANCE - MCI (Data Collection Only) - Miami
Georgia
- Emory University (Data Collection Only) - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 55 participants |
| Start Date | 2022-10-03 |
| Est. Completion | 2027-10 |
| Phase | Phase 2 |
What NCT05570253 shows while recruiting
NCT05570253 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 55 participants, a relatively small participant target, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with Breast Cancer appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT05570253 lists 10 locations in 4 states (New Jersey, New York, Florida).
Frequently Asked Questions
What is clinical trial NCT05570253 about?
NCT05570253 is a clinical study titled "A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer". The researchers are doing this study to find out whether the study drug, SDX-7320, when combined with the standard chemotherapy eribulin, is an effective treatment for people with TNBC and metabolic dysfunction. The researchers will also look at whether the study treatment (SDX-7320 combined with er...
What is the current status of trial NCT05570253?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 55 participants. The study started on 2022-10-03. Estimated completion is 2027-10.
What conditions does trial NCT05570253 study?
This clinical trial studies the following conditions: Breast Cancer, Metastatic Triple-Negative Breast Cancer.
What interventions are being tested in trial NCT05570253?
The interventions under investigation include: Placebo (OTHER), Eribulin (DRUG), SDX-7320 (DRUG).
Who is sponsoring clinical trial NCT05570253?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05570253 being conducted?
This trial has 10 study locations across Florida, Georgia, New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05570253's enrollment target sits among peer trials
55 767th of 1224 higher than 452 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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