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NCT07008105 · ClinicalTrials.gov registry record · NA
Comparing Single-Session Therapies for Chronic Pain
A NA study of Chronic Musculoskeletal Pain, sponsored by Mark A. Lumley.
- Recruiting
- Registry status
- NA
- Development phase
- 160
- Enrollment target
- 2
- Study locations
NCT07008105: Recruiting NA study of Chronic Musculoskeletal Pain, sponsored by Mark A. Lumley.
NCT07008105 is a NA study of Chronic Musculoskeletal Pain that is actively recruiting participants, run by Mark A. Lumley. The registered enrollment target is 160 participants, below the 423-participant average among 13 other Chronic Musculoskeletal Pain trials with a reported enrollment target (62% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07008105, a NA study of Chronic Musculoskeletal Pain, is actively recruiting participants, sponsored by Mark A. Lumley.
- RECRUITING
- Registry status
- NA
- Development phase
- 160 participants
- Enrollment target
- 2
- Study locations
Study Summary
Many people in the US suffer from chronic pain. Often times, individuals who have chronic pain also feel depressed, anxious, or hopeless, which can worsen pain. Psychologists, therefore, have developed several treatments to help people with chronic pain. These psychological treatments differ. The most common treatment is Cognitive Behavioral Therapy (CBT) for chronic pain, which helps patients better manage pain through changing thoughts and behaviors. Two newer, less common psychological therapies are Pain Reprocessing Therapy (PRT) and Emotion Awareness and Expression Therapy (EAET). These therapies emphasize that chronic pain is mainly due to plastic processes of over-sensitization in the brain and nervous system, and that psychotherapies can significantly reduce or eliminate pain. Although similar, PRT and EAET stress different aspects of treatment. PRT emphasizes that one's fear of pain and bodily injury maintains the brain's sense of threat, thereby also maintaining the pain response; EAET emphasizes that one's conditioned psychological state of stress and tension maintains a sense of threat, thereby maintaining the pain response. These three treatments have yet to be compared; it is unclear which psychological processes are most important to treating chronic pain. There is growing interest in single-session psychotherapy interventions. Studies have shown that just a single session of CBT or EAET can help individuals reduce their pain. PRT has yet to be condensed to a single-session intervention. This study will compare a single session of CBT, PRT, and EAET with a no-treatment control group to test whether 1) one treatment outperforms the others, and 2) different mechanisms/ approaches matter to chronic pain treatment.
Primary Outcome
4-item measure of pain severity over past week (range 0 to 10; higher scores = worse pain severity)
Conditions Studied
Interventions
- BEHAVIORAL Cognitive Behavioral Therapy
- BEHAVIORAL Pain Reprocessing Therapy
- BEHAVIORAL Emotion Awareness and Expression Therapy
Study Locations (2)
Illinois
- Rush University Medical Center - Chicago
Michigan
- Wayne State University - Detroit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 160 participants |
| Start Date | 2025-07-15 |
| Est. Completion | 2026-08 |
| Phase | NA |
What NCT07008105 shows while recruiting
NCT07008105 is an interventional study that assigns participants to a tested intervention. The registered 160 participants enrollment target is mid-sized for trials with a published cap, below the 423-participant average among 13 other Chronic Musculoskeletal Pain trials with a reported enrollment target (62% lower).
The record links to 1 condition, with Chronic Musculoskeletal Pain appearing as the primary indexed condition, and to 3 interventions - of which Cognitive Behavioral Therapy is the first listed.
NCT07008105 reports a single indexed study location in Illinois, Michigan.
Frequently Asked Questions
What is clinical trial NCT07008105 about?
NCT07008105 is a clinical study titled "Comparing Single-Session Therapies for Chronic Pain". Many people in the US suffer from chronic pain. Often times, individuals who have chronic pain also feel depressed, anxious, or hopeless, which can worsen pain. Psychologists, therefore, have developed several treatments to help people with chronic pain. These psychological treatments differ. The mo...
What is the current status of trial NCT07008105?
This trial is currently recruiting. It is a NA study. The enrollment target is 160 participants. The study started on 2025-07-15. Estimated completion is 2026-08.
What conditions does trial NCT07008105 study?
This clinical trial studies the following conditions: Chronic Musculoskeletal Pain.
What interventions are being tested in trial NCT07008105?
The interventions under investigation include: Cognitive Behavioral Therapy (BEHAVIORAL), Pain Reprocessing Therapy (BEHAVIORAL), Emotion Awareness and Expression Therapy (BEHAVIORAL).
Who is sponsoring clinical trial NCT07008105?
This trial is sponsored by Mark A. Lumley, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07008105 being conducted?
This trial has 2 study locations across Illinois, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Musculoskeletal Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07008105's enrollment target sits among peer trials
160 6th of 13 higher than 8 of 13 other Chronic Musculoskeletal Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Musculoskeletal Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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