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NCT03678025 · ClinicalTrials.gov registry record · Phase 3
Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer
A Phase 3 study of Stage IVB Prostate Cancer AJCC v8 and Stage IV Prostate Cancer AJCC v8, sponsored by SWOG Cancer Research Network.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 1,273
- Enrollment target
- 20
- Study locations
NCT03678025: Recruiting Phase 3 study of Stage IVB Prostate Cancer AJCC v8 and Stage IV Prostate Cancer AJCC v8, sponsored by SWOG Cancer Research Network.
NCT03678025 is a Phase 3 study of Stage IVB Prostate Cancer AJCC v8 and Stage IV Prostate Cancer AJCC v8 that is actively recruiting participants, run by SWOG Cancer Research Network. The registered enrollment target is 1,273 participants, above the 149-participant average among 45 other Stage IVB Prostate Cancer AJCC v8 trials with a reported enrollment target (754% higher). The trial reports 20 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03678025, a Phase 3 study of Stage IVB Prostate Cancer AJCC v8 and Stage IV Prostate Cancer AJCC v8, is actively recruiting participants, sponsored by SWOG Cancer Research Network.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 1,273 participants
- Enrollment target
- 20
- Study locations
Study Summary
This phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants with prostate cancer that has spread to other places in the body. Addition of prostate removal surgery or radiation therapy to standard systemic therapy for prostate cancer may lower the chance of the cancer growing or spreading.
Conditions Studied
Interventions
- DRUG Docetaxel
- DRUG Abiraterone
- DRUG Bicalutamide
- DRUG Degarelix
- DRUG Flutamide
Study Locations (20)
California
- Kaiser Permanente-Deer Valley Medical Center - Antioch
- Community Cancer Institute - Clovis
- University Oncology Associates - Clovis
- City of Hope Comprehensive Cancer Center - Duarte
- Kaiser Permanente Dublin - Dublin
- Kaiser Permanente-Fremont - Fremont
- Fresno Cancer Center - Fresno
- Kaiser Permanente-Fresno - Fresno
- UC San Diego Moores Cancer Center - La Jolla
- Tibor Rubin VA Medical Center - Long Beach
- Los Angeles County-USC Medical Center - Los Angeles
- USC / Norris Comprehensive Cancer Center - Los Angeles
- Fremont - Rideout Cancer Center - Marysville
Arizona
- Banner MD Anderson Cancer Center - Gilbert
- Cancer Center at Saint Joseph's - Phoenix
- Mayo Clinic Hospital in Arizona - Phoenix
- Mayo Clinic in Arizona - Scottsdale
- University of Arizona Cancer Center-Orange Grove Campus - Tucson
- University of Arizona Cancer Center-North Campus - Tucson
Arkansas
- University of Arkansas for Medical Sciences - Little Rock
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,273 participants |
| Start Date | 2018-09-24 |
| Est. Completion | 2031-10-01 |
| Phase | Phase 3 |
What NCT03678025 shows while recruiting
NCT03678025 is an interventional study that assigns participants to a tested intervention. Its 1,273 participants enrollment target places it among the larger protocols in the corpus, above the 149-participant average among 45 other Stage IVB Prostate Cancer AJCC v8 trials with a reported enrollment target (754% higher).
The record links to 5 conditions, with Stage IVB Prostate Cancer AJCC v8 appearing as the primary indexed condition, and to 5 interventions - of which Docetaxel is the first listed.
NCT03678025 names 20 study sites across 3 states, led by California, Arizona, Arkansas.
Frequently Asked Questions
What is clinical trial NCT03678025 about?
NCT03678025 is a clinical study titled "Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer". This phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants with prostate cancer that has spread to other places in the body. Addition of prostate removal surgery or radiation ther...
What is the current status of trial NCT03678025?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 1,273 participants. The study started on 2018-09-24. Estimated completion is 2031-10-01.
What conditions does trial NCT03678025 study?
This clinical trial studies the following conditions: Stage IVB Prostate Cancer AJCC v8, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Castration Levels of Testosterone, Metastatic Prostatic Adenocarcinoma.
What interventions are being tested in trial NCT03678025?
The interventions under investigation include: Docetaxel (DRUG), Abiraterone (DRUG), Bicalutamide (DRUG), Degarelix (DRUG), Flutamide (DRUG).
Who is sponsoring clinical trial NCT03678025?
This trial is sponsored by SWOG Cancer Research Network, which has 270 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03678025 being conducted?
This trial has 20 study locations across Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stage IVB Prostate Cancer AJCC v8
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03678025's enrollment target sits among peer trials
1,273 1st of 45 higher than 45 of 45 other Stage IVB Prostate Cancer AJCC v8 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stage IVB Prostate Cancer AJCC v8 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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