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NCT06999434 · ClinicalTrials.gov registry record · Phase 1

Exploring the Utility of [18F]3F4AP for Demyelination Imaging

A Phase 1 study of SCI - Spinal Cord Injury and MCI, sponsored by Yale University.

Recruiting
Registry status
Phase 1
Development phase
105
Enrollment target
1
Study location

NCT06999434 is a Phase 1 study of SCI - Spinal Cord Injury and MCI that is actively recruiting participants, run by Yale University. The registered enrollment target is 105 participants, above the 30-participant average among 13 other SCI - Spinal Cord Injury trials with a reported enrollment target (250% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT06999434, a Phase 1 study of SCI - Spinal Cord Injury and MCI, is actively recruiting participants, sponsored by Yale University.

RECRUITING
Registry status
Phase 1
Development phase
105 participants
Enrollment target
1
Study location

Study Summary

The overall objective is to obtain an assessment of the pharmacokinetics of \[18F\]3F4AP in healthy volunteers and subjects with demyelinating diseases such as mild cognitive impairment (MCI), Alzheimer's Disease (AD), Multiple Sclerosis (MS), Spinal Cord Injury (SCI) and Spinal radiculopathy (SR).

Conditions Studied

SCI - Spinal Cord Injury MCI Alzheimer's Disease (AD) MS (Multiple Sclerosis) Demyelinating Disorders Spinal Radiculopathy

Interventions

  • DRUG [ 18F]3F4AP
  • DRUG [18F]MK6240
  • DRUG [11C]PIB

Study Locations (1)

Connecticut

  • Yale University PET Center - New Haven

Trial Details

FieldValue
Enrollment Target 105 participants
Start Date 2025-05-05
Est. Completion 2030-05-05
Phase Phase 1

Sponsor

Yale University

1,492 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06999434

The ClinicalTrials.gov registry entry for NCT06999434 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 105 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 30-participant average among 13 other SCI - Spinal Cord Injury trials with a reported enrollment target (250% higher). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 6 conditions, with SCI - Spinal Cord Injury appearing as the primary indexed condition, and to 3 interventions - of which [ 18F]3F4AP is the first listed.

NCT06999434 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.

Frequently Asked Questions

What is clinical trial NCT06999434 about?

NCT06999434 is a clinical study titled "Exploring the Utility of [18F]3F4AP for Demyelination Imaging". The overall objective is to obtain an assessment of the pharmacokinetics of \[18F\]3F4AP in healthy volunteers and subjects with demyelinating diseases such as mild cognitive impairment (MCI), Alzheimer's Disease (AD), Multiple Sclerosis (MS), Spinal Cord Injury (SCI) and Spinal radiculopathy (SR).

What is the current status of trial NCT06999434?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 105 participants. The study started on 2025-05-05. Estimated completion is 2030-05-05.

What conditions does trial NCT06999434 study?

This clinical trial studies the following conditions: SCI - Spinal Cord Injury, MCI, Alzheimer's Disease (AD), MS (Multiple Sclerosis), Demyelinating Disorders.

What interventions are being tested in trial NCT06999434?

The interventions under investigation include: [ 18F]3F4AP (DRUG), [18F]MK6240 (DRUG), [11C]PIB (DRUG).

Who is sponsoring clinical trial NCT06999434?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06999434 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.