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NCT06853015 · ClinicalTrials.gov registry record · Phase 1

Double Dose 4-AP on Functional Recovery After Spinal Cord Injury

A Phase 1 study of SCI - Spinal Cord Injury, sponsored by Shirley Ryan AbilityLab.

Recruiting
Registry status
Phase 1
Development phase
27
Enrollment target
1
Study location

NCT06853015 is a Phase 1 study of SCI - Spinal Cord Injury that is actively recruiting participants, run by Shirley Ryan AbilityLab. The registered enrollment target is 27 participants, below the 36-participant average among 13 other SCI - Spinal Cord Injury trials with a reported enrollment target (25% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06853015, a Phase 1 study of SCI - Spinal Cord Injury, is actively recruiting participants, sponsored by Shirley Ryan AbilityLab.

RECRUITING
Registry status
Phase 1
Development phase
27 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to test a strategy to potentiate functional recovery of lower limb motor function in individuals with spinal cord injury (SCI). The FDA approved drug, Dalfampridine (4-AP). 4-AP will be used twice-daily in combination of Spike-timing-dependent plasticity (STDP) stimulation and STDP stimulation with limb training.

Conditions Studied

SCI - Spinal Cord Injury

Interventions

  • DRUG Placebo
  • BEHAVIORAL Exercise training
  • DRUG Dalfampridine
  • OTHER STDP stimulation

Study Locations (1)

Illinois

  • Shirley Ryan Abilitylab - Chicago

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2025-02-01
Est. Completion 2026-03
Phase Phase 1

Sponsor

Shirley Ryan AbilityLab

138 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06853015

The ClinicalTrials.gov registry entry for NCT06853015 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 27 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 36-participant average among 13 other SCI - Spinal Cord Injury trials with a reported enrollment target (25% lower). The listed sponsor is Shirley Ryan AbilityLab, which has 138 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with SCI - Spinal Cord Injury appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.

NCT06853015 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT06853015 about?

NCT06853015 is a clinical study titled "Double Dose 4-AP on Functional Recovery After Spinal Cord Injury". The purpose of this study is to test a strategy to potentiate functional recovery of lower limb motor function in individuals with spinal cord injury (SCI). The FDA approved drug, Dalfampridine (4-AP). 4-AP will be used twice-daily in combination of Spike-timing-dependent plasticity (STDP) stimulati...

What is the current status of trial NCT06853015?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 27 participants. The study started on 2025-02-01. Estimated completion is 2026-03.

What conditions does trial NCT06853015 study?

This clinical trial studies the following conditions: SCI - Spinal Cord Injury.

What interventions are being tested in trial NCT06853015?

The interventions under investigation include: Placebo (DRUG), Exercise training (BEHAVIORAL), Dalfampridine (DRUG), STDP stimulation (OTHER).

Who is sponsoring clinical trial NCT06853015?

This trial is sponsored by Shirley Ryan AbilityLab, which has 138 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06853015 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.