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NCT06922617 · ClinicalTrials.gov registry record · NA
STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking
A NA study of Substance Use Disorders and Tobacco Use, sponsored by Medical University of South Carolina.
- Recruiting
- Registry status
- NA
- Development phase
- 240
- Enrollment target
- 4
- Study locations
NCT06922617: Recruiting NA study of Substance Use Disorders and Tobacco Use, sponsored by Medical University of South Carolina.
NCT06922617 is a NA study of Substance Use Disorders and Tobacco Use that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 240 participants, below the 497-participant average among 93 other Substance Use Disorders trials with a reported enrollment target (52% lower). The trial reports 4 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06922617, a NA study of Substance Use Disorders and Tobacco Use, is actively recruiting participants, sponsored by Medical University of South Carolina.
- RECRUITING
- Registry status
- NA
- Development phase
- 240 participants
- Enrollment target
- 4
- Study locations
Study Summary
The purpose of this study is to investigate whether non-cigarette tobacco products, namely e-cigarettes (nicotine vapes), can help people who smoke and are in treatment for substance use disorder quit smoking by switching completely to e-cigarettes as compared to FDA-approved medications, namely nicotine replacement therapy in the form of patches and lozenges. Participation will last 6 months and will include five in-person study visits and eleven virtual assessments. Participants will also complete a short daily diary on their phones each day for the first twelve weeks. To qualify, participants must be within 30 days of SUD treatment program admission. This study is being conducted at three outpatient SUD treatment programs across South Carolina. These sites include: 1) the Center for Drug and Alcohol Problems (CDAP) in Charleston, SC, 2) Behavioral Health Services of Pickens County (BHSPC) in Pickens, SC, and 3) Shoreline Behavioral Health Services in Conway, SC. the Medical University of South Carolina in Charleston, SC, Behavioral Health Services in Pickens, SC, and the Medical University of South Carolina in Florence, SC.
Primary Outcome
7-day biologically confirmed point prevelance abstinence from cigarette smoking at Week 12 end of treatment visit
Conditions Studied
Interventions
- BEHAVIORAL Counseling
- BEHAVIORAL Switching to E-Cigarette
- DRUG Quitting using Medication
Study Locations (4)
South Carolina
- MUSC Charleston, Center for Drug and Alcohol Problems - Charleston
- Shoreline Behavioral Health Services - Conway
- Phoenix Center - Greenville
- Behavioral Health Services of Pickens County - Pickens
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 240 participants |
| Start Date | 2025-10-17 |
| Est. Completion | 2028-09-01 |
| Phase | NA |
What NCT06922617 shows while recruiting
NCT06922617 is an interventional study that assigns participants to a tested intervention. The registered 240 participants enrollment target is mid-sized for trials with a published cap, below the 497-participant average among 93 other Substance Use Disorders trials with a reported enrollment target (52% lower).
The record links to 2 conditions, with Substance Use Disorders appearing as the primary indexed condition, and to 3 interventions - of which Counseling is the first listed.
NCT06922617 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT06922617 about?
NCT06922617 is a clinical study titled "STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking". The purpose of this study is to investigate whether non-cigarette tobacco products, namely e-cigarettes (nicotine vapes), can help people who smoke and are in treatment for substance use disorder quit smoking by switching completely to e-cigarettes as compared to FDA-approved medications, namely nic...
What is the current status of trial NCT06922617?
This trial is currently recruiting. It is a NA study. The enrollment target is 240 participants. The study started on 2025-10-17. Estimated completion is 2028-09-01.
What conditions does trial NCT06922617 study?
This clinical trial studies the following conditions: Substance Use Disorders, Tobacco Use.
What interventions are being tested in trial NCT06922617?
The interventions under investigation include: Counseling (BEHAVIORAL), Switching to E-Cigarette (BEHAVIORAL), Quitting using Medication (DRUG).
Who is sponsoring clinical trial NCT06922617?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06922617 being conducted?
This trial has 4 study locations across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06922617's enrollment target sits among peer trials
240 28th of 93 higher than 65 of 93 other Substance Use Disorders trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Substance Use Disorders trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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