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NCT06922617 · ClinicalTrials.gov registry record · NA

STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking

A NA study of Substance Use Disorders and Tobacco Use, sponsored by Medical University of South Carolina.

Recruiting
Registry status
NA
Development phase
240
Enrollment target
4
Study locations

NCT06922617 is a NA study of Substance Use Disorders and Tobacco Use that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 240 participants, below the 497-participant average among 93 other Substance Use Disorders trials with a reported enrollment target (52% lower). The trial reports 4 study locations across 1 state.

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The verdict

NCT06922617, a NA study of Substance Use Disorders and Tobacco Use, is actively recruiting participants, sponsored by Medical University of South Carolina.

RECRUITING
Registry status
NA
Development phase
240 participants
Enrollment target
4
Study locations

Study Summary

The purpose of this study is to investigate whether non-cigarette tobacco products, namely e-cigarettes (nicotine vapes), can help people who smoke and are in treatment for substance use disorder quit smoking by switching completely to e-cigarettes as compared to FDA-approved medications, namely nicotine replacement therapy in the form of patches and lozenges. Participation will last 6 months and will include five in-person study visits and eleven virtual assessments. Participants will also complete a short daily diary on their phones each day for the first twelve weeks. To qualify, participants must be within 30 days of SUD treatment program admission. This study is being conducted at three outpatient SUD treatment programs across South Carolina. These sites include: 1) the Center for Drug and Alcohol Problems (CDAP) in Charleston, SC, 2) Behavioral Health Services of Pickens County (BHSPC) in Pickens, SC, and 3) Shoreline Behavioral Health Services in Conway, SC. the Medical University of South Carolina in Charleston, SC, Behavioral Health Services in Pickens, SC, and the Medical University of South Carolina in Florence, SC.

Conditions Studied

Substance Use Disorders Tobacco Use

Interventions

  • BEHAVIORAL Counseling
  • BEHAVIORAL Switching to E-Cigarette
  • DRUG Quitting using Medication

Study Locations (4)

South Carolina

  • MUSC Charleston, Center for Drug and Alcohol Problems - Charleston
  • Shoreline Behavioral Health Services - Conway
  • Phoenix Center - Greenville
  • Behavioral Health Services of Pickens County - Pickens

Trial Details

FieldValue
Enrollment Target 240 participants
Start Date 2025-10-17
Est. Completion 2028-09-01
Phase NA

Sponsor

Medical University of South Carolina

755 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06922617

The ClinicalTrials.gov registry entry for NCT06922617 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 240 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 497-participant average among 93 other Substance Use Disorders trials with a reported enrollment target (52% lower). The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Substance Use Disorders appearing as the primary indexed condition, and to 3 interventions - of which Counseling is the first listed.

NCT06922617 reports 4 study locations spanning 1 distinct geographic area - top geographies include South Carolina.

Frequently Asked Questions

What is clinical trial NCT06922617 about?

NCT06922617 is a clinical study titled "STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking". The purpose of this study is to investigate whether non-cigarette tobacco products, namely e-cigarettes (nicotine vapes), can help people who smoke and are in treatment for substance use disorder quit smoking by switching completely to e-cigarettes as compared to FDA-approved medications, namely nic...

What is the current status of trial NCT06922617?

This trial is currently recruiting. It is a NA study. The enrollment target is 240 participants. The study started on 2025-10-17. Estimated completion is 2028-09-01.

What conditions does trial NCT06922617 study?

This clinical trial studies the following conditions: Substance Use Disorders, Tobacco Use.

What interventions are being tested in trial NCT06922617?

The interventions under investigation include: Counseling (BEHAVIORAL), Switching to E-Cigarette (BEHAVIORAL), Quitting using Medication (DRUG).

Who is sponsoring clinical trial NCT06922617?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06922617 being conducted?

This trial has 4 study locations across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.