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NCT06873724 · ClinicalTrials.gov registry record · Phase 1

A Study of SPY003-207 in Healthy Volunteers

A Phase 1 study of Healthy, sponsored by Spyre Therapeutics.

Active
Registry status
Phase 1
Development phase
59
Enrollment target
2
Study locations

NCT06873724 is a Phase 1 study of Healthy that is active but no longer recruiting, run by Spyre Therapeutics. The registered enrollment target is 59 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (91% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT06873724, a Phase 1 study of Healthy, is active but no longer recruiting, sponsored by Spyre Therapeutics.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
59 participants
Enrollment target
2
Study locations

Study Summary

This is a Phase 1, randomized, double-blind, placebo-controlled, single dose, first in human safety, tolerability, and pharmacokinetic study of SPY003-207 in healthy participants.

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG SPY003-207

Study Locations (2)

California

  • Spyre Site 2 - Cypress

Quebec

  • Spyre Site 1 - Montreal

Trial Details

FieldValue
Enrollment Target 59 participants
Start Date 2025-03-10
Est. Completion 2026-11-18
Phase Phase 1

Sponsor

Spyre Therapeutics

6 total trials

What the Registry Record Tells You About NCT06873724

The ClinicalTrials.gov registry entry for NCT06873724 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 59 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (91% lower). The listed sponsor is Spyre Therapeutics, which has 6 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06873724 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, Quebec.

Frequently Asked Questions

What is clinical trial NCT06873724 about?

NCT06873724 is a clinical study titled "A Study of SPY003-207 in Healthy Volunteers". This is a Phase 1, randomized, double-blind, placebo-controlled, single dose, first in human safety, tolerability, and pharmacokinetic study of SPY003-207 in healthy participants.

What is the current status of trial NCT06873724?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 59 participants. The study started on 2025-03-10. Estimated completion is 2026-11-18.

What conditions does trial NCT06873724 study?

This clinical trial studies the following conditions: Healthy.

What interventions are being tested in trial NCT06873724?

The interventions under investigation include: Placebo (OTHER), SPY003-207 (DRUG).

Who is sponsoring clinical trial NCT06873724?

This trial is sponsored by Spyre Therapeutics, which has 6 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06873724 being conducted?

This trial has 2 study locations across California, Quebec. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.