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NCT06873724 · ClinicalTrials.gov registry record · Phase 1
A Study of SPY003-207 in Healthy Volunteers
A Phase 1 study of Healthy, sponsored by Spyre Therapeutics.
- Active
- Registry status
- Phase 1
- Development phase
- 59
- Enrollment target
- 2
- Study locations
NCT06873724: Active Phase 1 study of Healthy, sponsored by Spyre Therapeutics.
NCT06873724 is a Phase 1 study of Healthy that is active but no longer recruiting, run by Spyre Therapeutics. The registered enrollment target is 59 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (91% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06873724, a Phase 1 study of Healthy, is active but no longer recruiting, sponsored by Spyre Therapeutics.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 59 participants
- Enrollment target
- 2
- Study locations
Study Summary
This is a Phase 1, randomized, double-blind, placebo-controlled, single dose, first in human safety, tolerability, and pharmacokinetic study of SPY003-207 in healthy participants.
Primary Outcome
Incidence, severity, and causal relationship of TEAEs
Conditions Studied
Interventions
- OTHER Placebo
- DRUG SPY003-207
Study Locations (2)
California
- Spyre Site 2 - Cypress
Quebec
- Spyre Site 1 - Montreal
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 59 participants |
| Start Date | 2025-03-10 |
| Est. Completion | 2026-11-18 |
| Phase | Phase 1 |
What the registry record for NCT06873724 still lists
NCT06873724 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 59 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (91% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06873724 reports a single indexed study location in California, Quebec.
Frequently Asked Questions
What is clinical trial NCT06873724 about?
NCT06873724 is a clinical study titled "A Study of SPY003-207 in Healthy Volunteers". This is a Phase 1, randomized, double-blind, placebo-controlled, single dose, first in human safety, tolerability, and pharmacokinetic study of SPY003-207 in healthy participants.
What is the current status of trial NCT06873724?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 59 participants. The study started on 2025-03-10. Estimated completion is 2026-11-18.
What conditions does trial NCT06873724 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT06873724?
The interventions under investigation include: Placebo (OTHER), SPY003-207 (DRUG).
Who is sponsoring clinical trial NCT06873724?
This trial is sponsored by Spyre Therapeutics, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06873724 being conducted?
This trial has 2 study locations across California, Quebec. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06873724's enrollment target sits among peer trials
59 403rd of 1090 higher than 685 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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-
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RECRUITING · Phase 1
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