Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 2

Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer

NCT06850623 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of the study is to assess the efficacy and safety of Acoustic Cluster Therapy (ACT) when given in addition to chemotherapy for treatment of Locally Advanced Pancreatic Cancer.

Interventions

  • DRUG Modified FOLFIRINOX
  • COMBINATION_PRODUCT Acoustic Cluster Therapy

Study Locations (10)

Pennsylvania

  • Sidney Kimmel Cancer Center, Thomas Jefferson University Hospital — Philadelphia
  • Allegheny General Hospital — Pittsburgh

Arizona

  • HonorHealth Research Institute — Scottsdale

California

  • Stanford Cancer Center Palo Alto — Stanford

Massachusetts

  • Beth Israel Deaconess Medical Center - Division of Hematology/Oncology — Boston

Michigan

  • Henry Ford Centre — Detroit

Rhode Island

  • Brown University Cancer Institute — Providence

Cambridge

  • CAMBRIDGE CANCER TRIALS CENTRE-Addenbrooke's Hospital — Cambridge

London

  • Gary Weston Centre- Imperial College Healthcare- Du Cane Road — Hammersmith

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2025-06-19
Est. Completion 2027-07-15
Phase Phase 2

Sponsor

EXACT Therapeutics AS

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06850623

The ClinicalTrials.gov registry entry for NCT06850623 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is EXACT Therapeutics AS, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Locally Advanced Pancreatic Adenocarcinoma appearing as the primary indexed condition, and to 2 interventions — of which Modified FOLFIRINOX is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06850623 reports 10 study locations spanning 9 distinct geographic areas — top geographies include Pennsylvania, Arizona, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06850623 about?

NCT06850623 is a clinical study titled "Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer". The purpose of the study is to assess the efficacy and safety of Acoustic Cluster Therapy (ACT) when given in addition to chemotherapy for treatment of Locally Advanced Pancreatic Cancer.

What is the current status of trial NCT06850623?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2025-06-19. Estimated completion is 2027-07-15.

What conditions does trial NCT06850623 study?

This clinical trial studies the following conditions: Locally Advanced Pancreatic Adenocarcinoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06850623?

The interventions under investigation include: Modified FOLFIRINOX (DRUG), Acoustic Cluster Therapy (COMBINATION_PRODUCT). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06850623?

This trial is sponsored by EXACT Therapeutics AS, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06850623 being conducted?

This trial has 10 study locations across Arizona, California, Massachusetts, Michigan, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial