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NCT01897688 · ClinicalTrials.gov registry record · Phase 3

A Phase 3 Single Center Study of Islet Transplantation in Non-uremic Diabetic Patients

A Phase 3 study of Type 1 Diabetes and Severe Hypoglycemic Unawareness, sponsored by Northwestern University.

Active
Registry status
Phase 3
Development phase
40
Enrollment target
1
Study location

NCT01897688 is a Phase 3 study of Type 1 Diabetes and Severe Hypoglycemic Unawareness that is active but no longer recruiting, run by Northwestern University. The registered enrollment target is 40 participants, below the 824-participant average among 178 other Type 1 Diabetes trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01897688, a Phase 3 study of Type 1 Diabetes and Severe Hypoglycemic Unawareness, is active but no longer recruiting, sponsored by Northwestern University.

ACTIVE NOT RECRUITING
Registry status
Phase 3
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

Type 1 diabetes is an autoimmune disease in which the insulin-producing pancreatic beta cells are destroyed, resulting in poor blood sugar control. The purpose of this study is to determine the safety and effectiveness of islet transplantation, combined with immunosuppressive medications, specifically using Campath as induction, for treating type 1 diabetes in individuals experiencing hypoglycemia unawareness and severe hypoglycemic episodes.

Interventions

  • BIOLOGICAL Islet Cell Transplant

Study Locations (1)

Illinois

  • Northwestern University - Chicago

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2012-06
Est. Completion 2027-03
Phase Phase 3

Sponsor

Northwestern University

1,209 total trials

What the Registry Record Tells You About NCT01897688

The ClinicalTrials.gov registry entry for NCT01897688 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 824-participant average among 178 other Type 1 Diabetes trials with a reported enrollment target (95% lower). The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Type 1 Diabetes appearing as the primary indexed condition, and to 1 intervention - of which Islet Cell Transplant is the first listed.

NCT01897688 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT01897688 about?

NCT01897688 is a clinical study titled "A Phase 3 Single Center Study of Islet Transplantation in Non-uremic Diabetic Patients". Type 1 diabetes is an autoimmune disease in which the insulin-producing pancreatic beta cells are destroyed, resulting in poor blood sugar control. The purpose of this study is to determine the safety and effectiveness of islet transplantation, combined with immunosuppressive medications, specifical...

What is the current status of trial NCT01897688?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 40 participants. The study started on 2012-06. Estimated completion is 2027-03.

What conditions does trial NCT01897688 study?

This clinical trial studies the following conditions: Type 1 Diabetes, Severe Hypoglycemic Unawareness.

What interventions are being tested in trial NCT01897688?

The interventions under investigation include: Islet Cell Transplant (BIOLOGICAL).

Who is sponsoring clinical trial NCT01897688?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01897688 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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