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NCT01897688 · ClinicalTrials.gov registry record · Phase 3
A Phase 3 Single Center Study of Islet Transplantation in Non-uremic Diabetic Patients
A Phase 3 study of Type 1 Diabetes and Severe Hypoglycemic Unawareness, sponsored by Northwestern University.
- Active
- Registry status
- Phase 3
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT01897688: Active Phase 3 study of Type 1 Diabetes and Severe Hypoglycemic Unawareness, sponsored by Northwestern University.
NCT01897688 is a Phase 3 study of Type 1 Diabetes and Severe Hypoglycemic Unawareness that is active but no longer recruiting, run by Northwestern University. The registered enrollment target is 40 participants, below the 767-participant average among 198 other Type 1 Diabetes trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01897688, a Phase 3 study of Type 1 Diabetes and Severe Hypoglycemic Unawareness, is active but no longer recruiting, sponsored by Northwestern University.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Type 1 diabetes is an autoimmune disease in which the insulin-producing pancreatic beta cells are destroyed, resulting in poor blood sugar control. The purpose of this study is to determine the safety and effectiveness of islet transplantation, combined with immunosuppressive medications, specifically using Campath as induction, for treating type 1 diabetes in individuals experiencing hypoglycemia unawareness and severe hypoglycemic episodes.
Primary Outcome
Number of participants free of severe hypoglycemic events
Conditions Studied
Interventions
- BIOLOGICAL Islet Cell Transplant
Study Locations (1)
Illinois
- Northwestern University - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2012-06 |
| Est. Completion | 2027-03 |
| Phase | Phase 3 |
What the registry record for NCT01897688 still lists
NCT01897688 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 767-participant average among 198 other Type 1 Diabetes trials with a reported enrollment target (95% lower).
The record links to 2 conditions, with Type 1 Diabetes appearing as the primary indexed condition, and to 1 intervention - of which Islet Cell Transplant is the first listed.
NCT01897688 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT01897688 about?
NCT01897688 is a clinical study titled "A Phase 3 Single Center Study of Islet Transplantation in Non-uremic Diabetic Patients". Type 1 diabetes is an autoimmune disease in which the insulin-producing pancreatic beta cells are destroyed, resulting in poor blood sugar control. The purpose of this study is to determine the safety and effectiveness of islet transplantation, combined with immunosuppressive medications, specifical...
What is the current status of trial NCT01897688?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 40 participants. The study started on 2012-06. Estimated completion is 2027-03.
What conditions does trial NCT01897688 study?
This clinical trial studies the following conditions: Type 1 Diabetes, Severe Hypoglycemic Unawareness.
What interventions are being tested in trial NCT01897688?
The interventions under investigation include: Islet Cell Transplant (BIOLOGICAL).
Who is sponsoring clinical trial NCT01897688?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01897688 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Type 1 Diabetes
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01897688's enrollment target sits among peer trials
40 102nd of 198 higher than 92 of 198 other Type 1 Diabetes trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Type 1 Diabetes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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