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NCT06818968 · ClinicalTrials.gov registry record · Phase 1

A Study of the Effect of Multiple Doses of Diltiazem on the Plasma Levels of MK-6916 in Healthy Participants (MK-6916-005)

A Phase 1 study of Healthy, sponsored by Merck Sharp & Dohme.

Completed
Registry status
Phase 1
Development phase
37
Enrollment target
1
Study location

NCT06818968 is a Phase 1 study of Healthy that has completed, run by Merck Sharp & Dohme. The registered enrollment target is 37 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06818968, a Phase 1 study of Healthy, has completed, sponsored by Merck Sharp & Dohme.

COMPLETED
Registry status
Phase 1
Development phase
37 participants
Enrollment target
1
Study location

Study Summary

The goal of the study is to learn what happens to levels of MK-6916 in a healthy person's body over time. Researchers will compare what happens to MK-6916 in the body when it is given with or without another medicine called diltiazem.

Conditions Studied

Healthy

Interventions

  • DRUG Diltiazem
  • DRUG MK-6916

Study Locations (1)

Wisconsin

  • Fortrea CRU, Madison ( Site 0001) - Madison

Trial Details

FieldValue
Enrollment Target 37 participants
Start Date 2025-02-27
Est. Completion 2025-08-08
Phase Phase 1

Sponsor

Merck Sharp & Dohme

558 total trials

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What the Registry Record Tells You About NCT06818968

The ClinicalTrials.gov registry entry for NCT06818968 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 37 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (94% lower). The listed sponsor is Merck Sharp & Dohme, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Diltiazem is the first listed.

NCT06818968 reports 1 study location spanning 1 distinct geographic area - top geographies include Wisconsin.

Frequently Asked Questions

What is clinical trial NCT06818968 about?

NCT06818968 is a clinical study titled "A Study of the Effect of Multiple Doses of Diltiazem on the Plasma Levels of MK-6916 in Healthy Participants (MK-6916-005)". The goal of the study is to learn what happens to levels of MK-6916 in a healthy person's body over time. Researchers will compare what happens to MK-6916 in the body when it is given with or without another medicine called diltiazem.

What is the current status of trial NCT06818968?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 37 participants. The study started on 2025-02-27. Estimated completion is 2025-08-08.

What conditions does trial NCT06818968 study?

This clinical trial studies the following conditions: Healthy.

What interventions are being tested in trial NCT06818968?

The interventions under investigation include: Diltiazem (DRUG), MK-6916 (DRUG).

Who is sponsoring clinical trial NCT06818968?

This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06818968 being conducted?

This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.