Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT06817720 · ClinicalTrials.gov registry record · Phase 2

Phase II Study Assessing the Efficacy and Toxicity of Olverembatinib Monotherapy in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase

A Phase 2 study of Chronic Myeloid Leukemia, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
50
Enrollment target
1
Study location

NCT06817720: Recruiting Phase 2 study of Chronic Myeloid Leukemia, sponsored by M.D. Anderson Cancer Center.

NCT06817720 is a Phase 2 study of Chronic Myeloid Leukemia that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 50 participants, below the 209-participant average among 35 other Chronic Myeloid Leukemia trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT06817720, a Phase 2 study of Chronic Myeloid Leukemia, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
50 participants
Enrollment target
1
Study location

Study Summary

To learn if olverembatinib can help to control newly diagnosed CML in the chronic phase.

Primary Outcome

Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0

Conditions Studied

Interventions

  • DRUG olverembatinib

Study Locations (1)

Texas

  • MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2025-10-13
Est. Completion 2027-03-07
Phase Phase 2
M.D. Anderson Cancer Center

2,692 total trials

What NCT06817720 shows while recruiting

NCT06817720 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 209-participant average among 35 other Chronic Myeloid Leukemia trials with a reported enrollment target (76% lower).

The record links to 1 condition, with Chronic Myeloid Leukemia appearing as the primary indexed condition, and to 1 intervention - of which olverembatinib is the first listed.

NCT06817720 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT06817720 about?

NCT06817720 is a clinical study titled "Phase II Study Assessing the Efficacy and Toxicity of Olverembatinib Monotherapy in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase". To learn if olverembatinib can help to control newly diagnosed CML in the chronic phase.

What is the current status of trial NCT06817720?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2025-10-13. Estimated completion is 2027-03-07.

What conditions does trial NCT06817720 study?

This clinical trial studies the following conditions: Chronic Myeloid Leukemia.

What interventions are being tested in trial NCT06817720?

The interventions under investigation include: olverembatinib (DRUG).

Who is sponsoring clinical trial NCT06817720?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06817720 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Chronic Myeloid Leukemia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06817720's enrollment target sits among peer trials

50 19th of 35 higher than 16 of 35 other Chronic Myeloid Leukemia trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Chronic Myeloid Leukemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00200889 · 50 participants · Early Phase 1

    Mapping Auricular Vagus Nerve Circuitry

  • NCT00409435 · 50 participants · Phase 2

    A Study of Pyridostigmine in Postural Tachycardia Syndrome

  • NCT01202305 · 50 participants

    The Use of Lymph Node Biopsies to Support HIV Pathogenesis Studies

  • NCT01225913 · 50 participants · Phase 4

    Mechanism(s) of Airflow Limitation During Exacerbation of Asthma

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT06817720, the US trial registry maintained by the National Library of Medicine. NCT06817720 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.