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NCT06772779 · ClinicalTrials.gov registry record · Phase 1
A Study of Enlicitide Decanoate (MK-0616), Warfarin, and Lisinopril in Healthy Adult Participants (MK-0616-026)
A Phase 1 study, sponsored by Merck Sharp & Dohme.
- Completed
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
NCT06772779: Completed Phase 1 study, sponsored by Merck Sharp & Dohme.
NCT06772779 is a Phase 1 study that has completed, run by Merck Sharp & Dohme. The registered enrollment target is 36 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06772779, a Phase 1 study, has completed, sponsored by Merck Sharp & Dohme.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
Study Summary
The main goal of this study is to learn what happens in a person's body over time when they take enlicitide decanoate with warfarin or lisinopril. Researchers want to learn if the amount of warfarin in a person's blood is similar when warfarin is taken alone or with enlicitide decanoate. Enlicitide decanoate is a new medicine that lowers the amount of cholesterol in a person's blood. Warfarin is a drug that reduces risk of blood clotting, and lisinopril is a drug that lowers blood pressure.
Primary Outcome
Blood samples will be collected to determine the AUC0-Inf of warfarin.
Interventions
- DRUG Warfarin
- DRUG Enlicitide Decanoate
- DRUG Lisinopril
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2024-04-01 |
| Est. Completion | 2024-06-04 |
| Phase | Phase 1 |
What the finished NCT06772779 record still lists
NCT06772779 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower).
The record links to 0 conditions, and to 3 interventions - of which Warfarin is the first listed.
NCT06772779 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06772779 about?
NCT06772779 is a clinical study titled "A Study of Enlicitide Decanoate (MK-0616), Warfarin, and Lisinopril in Healthy Adult Participants (MK-0616-026)". The main goal of this study is to learn what happens in a person's body over time when they take enlicitide decanoate with warfarin or lisinopril. Researchers want to learn if the amount of warfarin in a person's blood is similar when warfarin is taken alone or with enlicitide decanoate. Enlicitide...
What is the current status of trial NCT06772779?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2024-04-01. Estimated completion is 2024-06-04.
What interventions are being tested in trial NCT06772779?
The interventions under investigation include: Warfarin (DRUG), Enlicitide Decanoate (DRUG), Lisinopril (DRUG).
Who is sponsoring clinical trial NCT06772779?
This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06772779's enrollment target sits among peer trials
36 1210th of 2000 higher than 743 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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