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NCT06772220 · ClinicalTrials.gov registry record · NA
Pilot Study of Open Label Homocysteine Management Therapy in Levodopa-treated Parkinson's Disease
A NA study of Parkinson's Disease, sponsored by Oregon Health and Science University.
- Recruiting
- Registry status
- NA
- Development phase
- 150
- Enrollment target
- 1
- Study location
NCT06772220: Recruiting NA study of Parkinson's Disease, sponsored by Oregon Health and Science University.
NCT06772220 is a NA study of Parkinson's Disease that is actively recruiting participants, run by Oregon Health and Science University. The registered enrollment target is 150 participants, below the 634-participant average among 158 other Parkinson's Disease trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06772220, a NA study of Parkinson's Disease, is actively recruiting participants, sponsored by Oregon Health and Science University.
- RECRUITING
- Registry status
- NA
- Development phase
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a research study investigating elevated homocysteine in the blood of patients with Parkinson's disease who are currently receiving treatment with levodopa. We are evaluating if elevated homocysteine can be corrected using open label B vitamin therapy, as well as the impact of homocysteine levels on cognitive function.
Primary Outcome
Plasma vitamin B12 in subjects with vs without hyperhomocysteinemia
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Folic Acid 1 MG
- DIETARY_SUPPLEMENT Vitamin B6 25 MG
- DIETARY_SUPPLEMENT Vitamin B12
Study Locations (1)
Oregon
- Oregon Health & Science University (OHSU) - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2024-03-05 |
| Est. Completion | 2025-12-31 |
| Phase | NA |
What NCT06772220 shows while recruiting
NCT06772220 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 634-participant average among 158 other Parkinson's Disease trials with a reported enrollment target (76% lower).
The record links to 1 condition, with Parkinson's Disease appearing as the primary indexed condition, and to 3 interventions - of which Folic Acid 1 MG is the first listed.
NCT06772220 reports a single indexed study location in Oregon.
Frequently Asked Questions
What is clinical trial NCT06772220 about?
NCT06772220 is a clinical study titled "Pilot Study of Open Label Homocysteine Management Therapy in Levodopa-treated Parkinson's Disease". This is a research study investigating elevated homocysteine in the blood of patients with Parkinson's disease who are currently receiving treatment with levodopa. We are evaluating if elevated homocysteine can be corrected using open label B vitamin therapy, as well as the impact of homocysteine le...
What is the current status of trial NCT06772220?
This trial is currently recruiting. It is a NA study. The enrollment target is 150 participants. The study started on 2024-03-05. Estimated completion is 2025-12-31.
What conditions does trial NCT06772220 study?
This clinical trial studies the following conditions: Parkinson's Disease.
What interventions are being tested in trial NCT06772220?
The interventions under investigation include: Folic Acid 1 MG (DIETARY_SUPPLEMENT), Vitamin B6 25 MG (DIETARY_SUPPLEMENT), Vitamin B12 (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT06772220?
This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06772220 being conducted?
This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06772220's enrollment target sits among peer trials
150 43rd of 158 higher than 115 of 158 other Parkinson's Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinson's Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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