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NCT05557864 · ClinicalTrials.gov registry record · NA
Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease
A NA study of Parkinson's Disease, sponsored by University of Minnesota.
- Recruiting
- Registry status
- NA
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT05557864: Recruiting NA study of Parkinson's Disease, sponsored by University of Minnesota.
NCT05557864 is a NA study of Parkinson's Disease that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 24 participants, below the 635-participant average among 158 other Parkinson's Disease trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05557864, a NA study of Parkinson's Disease, is actively recruiting participants, sponsored by University of Minnesota.
- RECRUITING
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
This protocol will characterize the effects of deep brain stimulation (DBS) location (both adverse and beneficial) on motor signs in people with Parkinson's disease (PD). This information can be used to inform future DBS protocols to tailor stimulation to the specific needs of a patient. If targeted dorsal GP stimulation is shown to significantly improve motor features that are typically resistant to dopamine replacement therapy, these experiments will likely have major impact on clinical practice by providing a potential strategy to these medically intractable symptoms.
Primary Outcome
Average movement rate and amplitude for each tone rate-movement amplitude interval. The amount of variability in angular displacement and velocity will be calculated using the root mean square of the zero mean signal. The structure of the variability will be calculated using the sample entropy function. In addition, we will quantify the number and duration of movement festination or freezing episodes.
Conditions Studied
Interventions
- DEVICE Deep Brain Stimulation
Study Locations (1)
Minnesota
- University Of Minnesota - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2016-08-25 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT05557864 shows while recruiting
NCT05557864 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 635-participant average among 158 other Parkinson's Disease trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Parkinson's Disease appearing as the primary indexed condition, and to 1 intervention - of which Deep Brain Stimulation is the first listed.
NCT05557864 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT05557864 about?
NCT05557864 is a clinical study titled "Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease". This protocol will characterize the effects of deep brain stimulation (DBS) location (both adverse and beneficial) on motor signs in people with Parkinson's disease (PD). This information can be used to inform future DBS protocols to tailor stimulation to the specific needs of a patient. If targeted...
What is the current status of trial NCT05557864?
This trial is currently recruiting. It is a NA study. The enrollment target is 24 participants. The study started on 2016-08-25. Estimated completion is 2026-12-31.
What conditions does trial NCT05557864 study?
This clinical trial studies the following conditions: Parkinson's Disease.
What interventions are being tested in trial NCT05557864?
The interventions under investigation include: Deep Brain Stimulation (DEVICE).
Who is sponsoring clinical trial NCT05557864?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05557864 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Parkinson's Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05557864's enrollment target sits among peer trials
24 119th of 158 higher than 38 of 158 other Parkinson's Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinson's Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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