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NCT06750549 · ClinicalTrials.gov registry record · NA
Mobile Application for Patient Engagement and Physician-Directed Remote Management of Heart Failure
A NA study of Heart Failure, sponsored by University of Michigan.
- Active
- Registry status
- NA
- Development phase
- 130
- Enrollment target
- 3
- Study locations
NCT06750549: Active NA study of Heart Failure, sponsored by University of Michigan.
NCT06750549 is a NA study of Heart Failure that is active but no longer recruiting, run by University of Michigan. The registered enrollment target is 130 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (94% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06750549, a NA study of Heart Failure, is active but no longer recruiting, sponsored by University of Michigan.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 130 participants
- Enrollment target
- 3
- Study locations
Study Summary
The ENGAGE-HF mobile application tracks three key features over time: (1) heart failure health status, (2) vital signs (e.g., blood pressure, heart rate) and weight, and (3) the quality of heart failure medication therapy. Helping patients understand how these characteristics interact and change over time may improve their ability to understand and manage heart failure. In this study, the investigators aim to evaluate whether the ENGAGE-HF mobile application, by facilitating the behavior change strategies of self-monitoring and feedback, and a clinician-facing dashboard, improves the optimization of heart failure guideline-directed medical therapies (GDMT) and quality of life. An optional sub-study of cognitive function will invite all eligible participants enrolled in the main study to participate.
Primary Outcome
The primary outcome will be the difference in the medication optimization score at 90 days between the intervention and control group. The MOS is a percent between 0 (least optimized) and 100 (most optimized), which represents the extent of medication optimization that needs to be performed. Inputs for the score include medications, vital signs, and laboratory values, and thus, the score accounts for contraindications to medical therapy titration. The score has been shown to correlate with clini
Conditions Studied
Interventions
- DEVICE ENGAGE-HF Mobile Application
Study Locations (3)
California
- Stanford Cardiovascular Clinic - Stanford
Maryland
- The Johns Hopkins Hospital - Baltimore
Michigan
- U-M Frankel Cardiovascular Center - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2025-02-18 |
| Est. Completion | 2026-05-31 |
| Phase | NA |
What the registry record for NCT06750549 still lists
NCT06750549 is an interventional study that assigns participants to a tested intervention. The registered 130 participants enrollment target is mid-sized for trials with a published cap, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Heart Failure appearing as the primary indexed condition, and to 1 intervention - of which ENGAGE-HF Mobile Application is the first listed.
NCT06750549 reports a single indexed study location in California, Maryland, Michigan.
Frequently Asked Questions
What is clinical trial NCT06750549 about?
NCT06750549 is a clinical study titled "Mobile Application for Patient Engagement and Physician-Directed Remote Management of Heart Failure". The ENGAGE-HF mobile application tracks three key features over time: (1) heart failure health status, (2) vital signs (e.g., blood pressure, heart rate) and weight, and (3) the quality of heart failure medication therapy. Helping patients understand how these characteristics interact and change ove...
What is the current status of trial NCT06750549?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 130 participants. The study started on 2025-02-18. Estimated completion is 2026-05-31.
What conditions does trial NCT06750549 study?
This clinical trial studies the following conditions: Heart Failure.
What interventions are being tested in trial NCT06750549?
The interventions under investigation include: ENGAGE-HF Mobile Application (DEVICE).
Who is sponsoring clinical trial NCT06750549?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06750549 being conducted?
This trial has 3 study locations across California, Maryland, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06750549's enrollment target sits among peer trials
130 196th of 397 higher than 200 of 397 other Heart Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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