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NCT06689176 · ClinicalTrials.gov registry record · NA

Chlorhexidine Antiseptic Irrigation of the Bowel Segment During Radical Cystectomy and Urinary Diversion

A NA study of Bladder Cancer and Urinary Tract Infection, sponsored by Icahn School of Medicine at Mount Sinai.

Recruiting
Registry status
NA
Development phase
23
Enrollment target
1
Study location

NCT06689176: Recruiting NA study of Bladder Cancer and Urinary Tract Infection, sponsored by Icahn School of Medicine at Mount Sinai.

NCT06689176 is a NA study of Bladder Cancer and Urinary Tract Infection that is actively recruiting participants, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 23 participants, below the 12,754-participant average among 175 other Bladder Cancer trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06689176, a NA study of Bladder Cancer and Urinary Tract Infection, is actively recruiting participants, sponsored by Icahn School of Medicine at Mount Sinai.

RECRUITING
Registry status
NA
Development phase
23 participants
Enrollment target
1
Study location

Study Summary

This is a single arm, interventional pilot study of using chlorhexidine irrigation intra-operatively and post-operatively among patients undergoing radical cystectomy with urinary diversion. The intervention comprises of using irrigation of ileal conduit or ileal neobladder intra-operatively and then for irrigation of either post-surgery with Irrisept ®. The sterilization of urine will be assessed at 10 days after cystectomy. Incidence of symptomatic urinary tract infections within the 30-day post-operative period will be estimated.

Primary Outcome

Negative urine culture will be defined as a colony count of less than or equal to 100000 CFU/ml. The urine sample will be collected by catheterization of the conduit with a 16F Foley catheter, which provides the least number of CFU of bacteria compared to collection from the ostomy bag. Patients with ileal neobladder will give a spontaneously voided urine sample when able or will be obtained from catheterized urine for those who cannot void.

Interventions

  • DEVICE Irrisept® Antimicrobial Wound Lavage

Study Locations (1)

New York

  • Mount Sinai Hospital - New York

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2024-08-01
Est. Completion 2026-07-01
Phase NA

What NCT06689176 shows while recruiting

NCT06689176 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 12,754-participant average among 175 other Bladder Cancer trials with a reported enrollment target (100% lower).

The record links to 2 conditions, with Bladder Cancer appearing as the primary indexed condition, and to 1 intervention - of which Irrisept® Antimicrobial Wound Lavage is the first listed.

NCT06689176 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT06689176 about?

NCT06689176 is a clinical study titled "Chlorhexidine Antiseptic Irrigation of the Bowel Segment During Radical Cystectomy and Urinary Diversion". This is a single arm, interventional pilot study of using chlorhexidine irrigation intra-operatively and post-operatively among patients undergoing radical cystectomy with urinary diversion. The intervention comprises of using irrigation of ileal conduit or ileal neobladder intra-operatively and the...

What is the current status of trial NCT06689176?

This trial is currently recruiting. It is a NA study. The enrollment target is 23 participants. The study started on 2024-08-01. Estimated completion is 2026-07-01.

What conditions does trial NCT06689176 study?

This clinical trial studies the following conditions: Bladder Cancer, Urinary Tract Infection.

What interventions are being tested in trial NCT06689176?

The interventions under investigation include: Irrisept® Antimicrobial Wound Lavage (DEVICE).

Who is sponsoring clinical trial NCT06689176?

This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06689176 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Bladder Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06689176's enrollment target sits among peer trials

23 147th of 175 higher than 29 of 175 other Bladder Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Bladder Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06689176, the US trial registry maintained by the National Library of Medicine. NCT06689176 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.