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NCT06685068 · ClinicalTrials.gov registry record · Phase 1

A Phase 1/2 Study of GEN1286 in Patients With Advanced Solid Tumors

A Phase 1 study of Advanced Solid Tumor, sponsored by Genmab.

Active
Registry status
Phase 1
Development phase
23
Enrollment target
4
Study locations

NCT06685068 is a Phase 1 study of Advanced Solid Tumor that is active but no longer recruiting, run by Genmab. The registered enrollment target is 23 participants, below the 193-participant average among 189 other Advanced Solid Tumor trials with a reported enrollment target (88% lower). The trial reports 4 study locations across 4 states.

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The verdict

NCT06685068, a Phase 1 study of Advanced Solid Tumor, is active but no longer recruiting, sponsored by Genmab.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
23 participants
Enrollment target
4
Study locations

Study Summary

The purpose of this trial is to evaluate the safety, tolerability, pharmacokinetics (PK), anti-tumor activity and immunogenic potential of GEN1286 in participants with advanced solid tumors. This trial consists of 2 parts: * Part A: Dose escalation and dose level expansion * Part B: Tumor-specific expansion with dose optimization

Conditions Studied

Advanced Solid Tumor

Interventions

  • DRUG GEN1286

Study Locations (4)

Massachusetts

  • Massachusetts General Hospital - Boston

Michigan

  • START Midwest - Grand Rapids

Texas

  • START San Antonio - San Antonio

Utah

  • START Mountain Region - West Valley City

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2024-11-13
Est. Completion 2028-06-29
Phase Phase 1

Sponsor

Genmab

45 total trials

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What the Registry Record Tells You About NCT06685068

The ClinicalTrials.gov registry entry for NCT06685068 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 23 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 193-participant average among 189 other Advanced Solid Tumor trials with a reported enrollment target (88% lower). The listed sponsor is Genmab, which has 45 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Advanced Solid Tumor appearing as the primary indexed condition, and to 1 intervention - of which GEN1286 is the first listed.

NCT06685068 reports 4 study locations spanning 4 distinct geographic areas - top geographies include Massachusetts, Michigan, Texas.

Frequently Asked Questions

What is clinical trial NCT06685068 about?

NCT06685068 is a clinical study titled "A Phase 1/2 Study of GEN1286 in Patients With Advanced Solid Tumors". The purpose of this trial is to evaluate the safety, tolerability, pharmacokinetics (PK), anti-tumor activity and immunogenic potential of GEN1286 in participants with advanced solid tumors. This trial consists of 2 parts: * Part A: Dose escalation and dose level expansion * Part B: Tumor-specific...

What is the current status of trial NCT06685068?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2024-11-13. Estimated completion is 2028-06-29.

What conditions does trial NCT06685068 study?

This clinical trial studies the following conditions: Advanced Solid Tumor.

What interventions are being tested in trial NCT06685068?

The interventions under investigation include: GEN1286 (DRUG).

Who is sponsoring clinical trial NCT06685068?

This trial is sponsored by Genmab, which has 45 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06685068 being conducted?

This trial has 4 study locations across Massachusetts, Michigan, Texas, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.