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NCT06680232 · ClinicalTrials.gov registry record · Phase 1
Phase 1 Study to Evaluate Safety and Antiviral Activity of PBGENE-HBV in Adult Patients With Chronic Hepatitis B
A Phase 1 study of Hepatitis B， Chronic, sponsored by Precision BioSciences.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 45
- Enrollment target
- 4
- Study locations
NCT06680232 is a Phase 1 study of Hepatitis B， Chronic that is actively recruiting participants, run by Precision BioSciences. The registered enrollment target is 45 participants, below the 599-participant average among 6 other Hepatitis B， Chronic trials with a reported enrollment target (92% lower). The trial reports 4 study locations across 3 states.
The verdict
NCT06680232, a Phase 1 study of Hepatitis B， Chronic, is actively recruiting participants, sponsored by Precision BioSciences.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 45 participants
- Enrollment target
- 4
- Study locations
Study Summary
This is a Phase 1, open-label, dose escalation and dose expansion study to evaluate the safety, tolerability, PK, and antiviral activity of PBGENE-HBV in adult participants with chronic hepatitis B.
Conditions Studied
Interventions
- BIOLOGICAL PBGENE-HBV
Study Locations (4)
Other
- ICS ARENSIA Exploratory Medicine SRL - Chisinau
- New Zealand Clinical Research - Auckland
Massachusetts
- Massachusetts General Hospital/Harvard University - Boston
Hong Kong
- Queen Mary Hospital, The University of Hong Kong - Hong Kong
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2024-11-14 |
| Est. Completion | 2026-12 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06680232
The ClinicalTrials.gov registry entry for NCT06680232 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 599-participant average among 6 other Hepatitis B， Chronic trials with a reported enrollment target (92% lower). The listed sponsor is Precision BioSciences, which has 5 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Hepatitis B， Chronic appearing as the primary indexed condition, and to 1 intervention - of which PBGENE-HBV is the first listed.
NCT06680232 reports 4 study locations spanning 3 distinct geographic areas - top geographies include Other, Massachusetts, Hong Kong.
Frequently Asked Questions
What is clinical trial NCT06680232 about?
NCT06680232 is a clinical study titled "Phase 1 Study to Evaluate Safety and Antiviral Activity of PBGENE-HBV in Adult Patients With Chronic Hepatitis B". This is a Phase 1, open-label, dose escalation and dose expansion study to evaluate the safety, tolerability, PK, and antiviral activity of PBGENE-HBV in adult participants with chronic hepatitis B.
What is the current status of trial NCT06680232?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 45 participants. The study started on 2024-11-14. Estimated completion is 2026-12.
What conditions does trial NCT06680232 study?
This clinical trial studies the following conditions: Hepatitis B， Chronic.
What interventions are being tested in trial NCT06680232?
The interventions under investigation include: PBGENE-HBV (BIOLOGICAL).
Who is sponsoring clinical trial NCT06680232?
This trial is sponsored by Precision BioSciences, which has 5 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06680232 being conducted?
This trial has 4 study locations across Massachusetts, Hong Kong. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.