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NCT06606327 · ClinicalTrials.gov registry record · Phase 1
Diazoxide Suppression Test P&F Study
A Phase 1 study of Obesity and Insulin Resistance, sponsored by Columbia University.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT06606327: Recruiting Phase 1 study of Obesity and Insulin Resistance, sponsored by Columbia University.
NCT06606327 is a Phase 1 study of Obesity and Insulin Resistance that is actively recruiting participants, run by Columbia University. The registered enrollment target is 10 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06606327, a Phase 1 study of Obesity and Insulin Resistance, is actively recruiting participants, sponsored by Columbia University.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to learn about how the hormone insulin controls blood sugar. The main question it aims to answer is about how much insulin the body actually needs to maintain a normal blood sugar level. People with obesity and high insulin levels will receive eight doses of diazoxide, a drug that suppresses the pancreas's production of insulin, and will have their fasting blood sugar and insulin levels checked daily while taking the drug.
Primary Outcome
Plasma glucose level after overnight fast (units: mg/dL)
Conditions Studied
Interventions
- DRUG Diazoxide, 3 mg/kg per dose
Study Locations (1)
New York
- Columbia University Irving Medical Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2024-10-23 |
| Est. Completion | 2028-01 |
| Phase | Phase 1 |
What NCT06606327 shows while recruiting
NCT06606327 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (99% lower).
The record links to 3 conditions, with Obesity appearing as the primary indexed condition, and to 1 intervention - of which Diazoxide, 3 mg/kg per dose is the first listed.
NCT06606327 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT06606327 about?
NCT06606327 is a clinical study titled "Diazoxide Suppression Test P&F Study". The goal of this study is to learn about how the hormone insulin controls blood sugar. The main question it aims to answer is about how much insulin the body actually needs to maintain a normal blood sugar level. People with obesity and high insulin levels will receive eight doses of diazoxide, a dr...
What is the current status of trial NCT06606327?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2024-10-23. Estimated completion is 2028-01.
What conditions does trial NCT06606327 study?
This clinical trial studies the following conditions: Obesity, Insulin Resistance, Hyperinsulinemia.
What interventions are being tested in trial NCT06606327?
The interventions under investigation include: Diazoxide, 3 mg/kg per dose (DRUG).
Who is sponsoring clinical trial NCT06606327?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06606327 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06606327's enrollment target sits among peer trials
10 1025th of 1053 higher than 19 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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