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NCT06589362 · ClinicalTrials.gov registry record · NA
Noninvasive Vagal Nerve Stimulation and Cognitive Rehabilitation
A NA study of Traumatic Brain Injury, sponsored by Shirley Ryan AbilityLab.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06589362: Recruiting NA study of Traumatic Brain Injury, sponsored by Shirley Ryan AbilityLab.
NCT06589362 is a NA study of Traumatic Brain Injury that is actively recruiting participants, run by Shirley Ryan AbilityLab. The registered enrollment target is 60 participants, below the 277-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06589362, a NA study of Traumatic Brain Injury, is actively recruiting participants, sponsored by Shirley Ryan AbilityLab.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to examine the feasibility and preliminary efficacy of using transcutaneous auricular vagus nerve stimulation (tVNS) to enhance cognitive recovery in patients with mild-moderate traumatic brain injury (TBI).
Primary Outcome
In the n-back task, participants are presented a series of visual stimuli. They are asked for each stimulus whether it matches a stimulus n trials before. For example, in a 2-back task, in which the trials consist of letters, participants have to decide whether the current letter is the same as the letter in trial n - 2. We will use a computerized version of this task.
Conditions Studied
Interventions
- DEVICE Transcutaneous auricular vagus active nerve stimulation
- DEVICE Transcutaneous auricular vagus sham nerve stimulation
Study Locations (1)
Illinois
- Shirley Ryan AbilityLab - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2024-09-07 |
| Est. Completion | 2026-08 |
| Phase | NA |
What NCT06589362 shows while recruiting
NCT06589362 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 277-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target (78% lower).
The record links to 1 condition, with Traumatic Brain Injury appearing as the primary indexed condition, and to 2 interventions - of which Transcutaneous auricular vagus active nerve stimulation is the first listed.
NCT06589362 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT06589362 about?
NCT06589362 is a clinical study titled "Noninvasive Vagal Nerve Stimulation and Cognitive Rehabilitation". The purpose of this study is to examine the feasibility and preliminary efficacy of using transcutaneous auricular vagus nerve stimulation (tVNS) to enhance cognitive recovery in patients with mild-moderate traumatic brain injury (TBI).
What is the current status of trial NCT06589362?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2024-09-07. Estimated completion is 2026-08.
What conditions does trial NCT06589362 study?
This clinical trial studies the following conditions: Traumatic Brain Injury.
What interventions are being tested in trial NCT06589362?
The interventions under investigation include: Transcutaneous auricular vagus active nerve stimulation (DEVICE), Transcutaneous auricular vagus sham nerve stimulation (DEVICE).
Who is sponsoring clinical trial NCT06589362?
This trial is sponsored by Shirley Ryan AbilityLab, which has 138 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06589362 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Traumatic Brain Injury
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06589362's enrollment target sits among peer trials
60 103rd of 171 higher than 61 of 171 other Traumatic Brain Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Traumatic Brain Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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