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NCT06585254 · ClinicalTrials.gov registry record · NA
tVNS in Long COVID-19
A NA study of Long COVID and Chronic Fatigue Syndrome, sponsored by Icahn School of Medicine at Mount Sinai.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT06585254: Recruiting NA study of Long COVID and Chronic Fatigue Syndrome, sponsored by Icahn School of Medicine at Mount Sinai.
NCT06585254 is a NA study of Long COVID and Chronic Fatigue Syndrome that is actively recruiting participants, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 50 participants, below the 2,187-participant average among 50 other Long COVID trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06585254, a NA study of Long COVID and Chronic Fatigue Syndrome, is actively recruiting participants, sponsored by Icahn School of Medicine at Mount Sinai.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
A prior open label study has shown that transcutaneous vagus nerve stimulation \[tVNS\] can improve the health of some patients with postacute sequelae of SARS-CoV-2 infection (PASC), severely affected enough to also fulfill criteria for myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS). The purpose of this study is to compare two sets of stimulus parameters to determine the one that best improves the health-related quality of life of these patients over a period of 6-weeks. Patients using their assigned device for at least 30 of the 42 possible opportunities will receive the best device for an additional 6-week period.
Primary Outcome
The Chalder Fatigue Questionnaire (CFQ) is used as a measure of fatigue. The CFQ consists of 11 items and uses likert scoring 0, 1, 2, 3, providing a full scale range of 0-33, where lowest score is least fatigue.
Conditions Studied
Interventions
- DEVICE Transcutaneous vagus nerve stimulator
Study Locations (1)
New York
- Icahn School of Medicine at Mount Sinai - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2024-11-01 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT06585254 shows while recruiting
NCT06585254 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 2,187-participant average among 50 other Long COVID trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with Long COVID appearing as the primary indexed condition, and to 1 intervention - of which Transcutaneous vagus nerve stimulator is the first listed.
NCT06585254 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT06585254 about?
NCT06585254 is a clinical study titled "tVNS in Long COVID-19". A prior open label study has shown that transcutaneous vagus nerve stimulation \[tVNS\] can improve the health of some patients with postacute sequelae of SARS-CoV-2 infection (PASC), severely affected enough to also fulfill criteria for myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS)....
What is the current status of trial NCT06585254?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2024-11-01. Estimated completion is 2026-12-31.
What conditions does trial NCT06585254 study?
This clinical trial studies the following conditions: Long COVID, Chronic Fatigue Syndrome.
What interventions are being tested in trial NCT06585254?
The interventions under investigation include: Transcutaneous vagus nerve stimulator (DEVICE).
Who is sponsoring clinical trial NCT06585254?
This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06585254 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Long COVID
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06585254's enrollment target sits among peer trials
50 34th of 50 higher than 16 of 50 other Long COVID trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Long COVID trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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