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NCT06555744 · ClinicalTrials.gov registry record · Phase 1

A Study of ZW191 in Participants With Solid Tumors

A Phase 1 study of Advanced Solid Tumors, sponsored by Zymeworks BC.

Recruiting
Registry status
Phase 1
Development phase
145
Enrollment target
20
Study locations

NCT06555744 is a Phase 1 study of Advanced Solid Tumors that is actively recruiting participants, run by Zymeworks BC. The registered enrollment target is 145 participants, below the 198-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (27% lower). The trial reports 20 study locations across 6 states.

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The verdict

NCT06555744, a Phase 1 study of Advanced Solid Tumors, is actively recruiting participants, sponsored by Zymeworks BC.

RECRUITING
Registry status
Phase 1
Development phase
145 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to find out if ZW191 is safe and can treat participants with advanced cancers, including ovarian, endometrial, and non-small cell lung cancers.

Conditions Studied

Advanced Solid Tumors

Interventions

  • DRUG ZW191

Study Locations (20)

Other

  • Linear Clinical Research - Nedlands
  • Royal North Shore Hospital Northern Sydney Cancer Centre - St Leonards
  • National Cancer Center Hospital East - Kashiwa-shi
  • Saitama Medical University International Medical Center - Saitama
  • National Cancer Center Hospital - Tokyo
  • The Cancer Institute Hospital of JFCR - Tokyo
  • National University Health System (NUHS) - National University Cancer Institute Singapore (NCIS) - Singapore
  • National Cancer Centre Singapore - Singapore
  • Curie Oncology - Singapore
  • National Cancer Center - Goyang-si
  • Seoul National University Bundang Hospital - Seongnam-si
  • Seoul National University Hospital - Seoul
  • Severance Hospital, Yonsei University Health System - Seoul
  • Asan Medical Center - Seoul
  • Samsung Medical Center - Seoul

Connecticut

  • Yale University - New Haven

Ohio

  • The Arthur G. James Cancer Hospital and Richard J. Solove Research Institute - Columbus

Oklahoma

  • Stephenson Cancer Center - Oklahoma City

Texas

  • NEXT Oncology - San Antonio

Virginia

  • NEXT Virginia - Fairfax

Trial Details

FieldValue
Enrollment Target 145 participants
Start Date 2024-10-30
Est. Completion 2027-01
Phase Phase 1

Sponsor

Zymeworks BC

4 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06555744

The ClinicalTrials.gov registry entry for NCT06555744 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 145 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 198-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (27% lower). The listed sponsor is Zymeworks BC, which has 4 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Advanced Solid Tumors appearing as the primary indexed condition, and to 1 intervention - of which ZW191 is the first listed.

NCT06555744 reports 20 study locations spanning 6 distinct geographic areas - top geographies include Other, Connecticut, Ohio.

Frequently Asked Questions

What is clinical trial NCT06555744 about?

NCT06555744 is a clinical study titled "A Study of ZW191 in Participants With Solid Tumors". The purpose of this study is to find out if ZW191 is safe and can treat participants with advanced cancers, including ovarian, endometrial, and non-small cell lung cancers.

What is the current status of trial NCT06555744?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 145 participants. The study started on 2024-10-30. Estimated completion is 2027-01.

What conditions does trial NCT06555744 study?

This clinical trial studies the following conditions: Advanced Solid Tumors.

What interventions are being tested in trial NCT06555744?

The interventions under investigation include: ZW191 (DRUG).

Who is sponsoring clinical trial NCT06555744?

This trial is sponsored by Zymeworks BC, which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06555744 being conducted?

This trial has 20 study locations across Connecticut, Ohio, Oklahoma, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.