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NCT05708274 · ClinicalTrials.gov registry record · Phase 1
Pharmacological Agents for Chronic Spinal Cord Injury (SCI)
A Phase 1 study of Spinal Cord Injuries, sponsored by Bronx VA Medical Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 25
- Enrollment target
- 1
- Study location
NCT05708274 is a Phase 1 study of Spinal Cord Injuries that has completed, run by Bronx VA Medical Center. The registered enrollment target is 25 participants, below the 61-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (59% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05708274, a Phase 1 study of Spinal Cord Injuries, has completed, sponsored by Bronx VA Medical Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to investigate the short-term effects of 3 approved FDA drugs (cyproheptadine (CPH), carbidopa-levodopa (CD-LD), and atomoxetine (ATX)) on motor responses when delivered in combination with hand training exercises in people with chronic spinal cord injury. The goal is to learn how to better strengthen connections between the brain and spinal cord after spinal cord injury, and if this connection is improved by one(or more) of the drugs. Multiple aspects of nerve transmission and muscle response will be measured via noninvasive brain and spinal cord stimulation, along with motor performance (dexterity and strength).
Conditions Studied
Interventions
- DRUG CPH + hand training
- DRUG CD-LD + hand training
- DRUG ATX + hand training
- DRUG Placebo + hand training
Study Locations (1)
New York
- James J. Peters Veterans Affairs Medical Center - The Bronx
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2023-01-20 |
| Est. Completion | 2025-10-30 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05708274
The ClinicalTrials.gov registry entry for NCT05708274 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 61-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (59% lower). The listed sponsor is Bronx VA Medical Center, which has 13 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Spinal Cord Injuries appearing as the primary indexed condition, and to 4 interventions - of which CPH + hand training is the first listed.
NCT05708274 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.
Frequently Asked Questions
What is clinical trial NCT05708274 about?
NCT05708274 is a clinical study titled "Pharmacological Agents for Chronic Spinal Cord Injury (SCI)". The purpose of this study is to investigate the short-term effects of 3 approved FDA drugs (cyproheptadine (CPH), carbidopa-levodopa (CD-LD), and atomoxetine (ATX)) on motor responses when delivered in combination with hand training exercises in people with chronic spinal cord injury. The goal is to...
What is the current status of trial NCT05708274?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2023-01-20. Estimated completion is 2025-10-30.
What conditions does trial NCT05708274 study?
This clinical trial studies the following conditions: Spinal Cord Injuries.
What interventions are being tested in trial NCT05708274?
The interventions under investigation include: CPH + hand training (DRUG), CD-LD + hand training (DRUG), ATX + hand training (DRUG), Placebo + hand training (DRUG).
Who is sponsoring clinical trial NCT05708274?
This trial is sponsored by Bronx VA Medical Center, which has 13 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05708274 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.