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NCT06427538 · ClinicalTrials.gov registry record · NA
Chest Drain Regular Flushing in Complicated Parapneumonic Effusions and Empyemas
A NA study of Pleural Infection and Empyema, Pleural, sponsored by Vanderbilt University Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 96
- Enrollment target
- 5
- Study locations
NCT06427538: Recruiting NA study of Pleural Infection and Empyema, Pleural, sponsored by Vanderbilt University Medical Center.
NCT06427538 is a NA study of Pleural Infection and Empyema, Pleural that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 96 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). The trial reports 5 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06427538, a NA study of Pleural Infection and Empyema, Pleural, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 96 participants
- Enrollment target
- 5
- Study locations
Study Summary
Infections of the pleural space are common, and patients require antibiotics and chest drain placement to evacuate the chest from the infected fluid. Chest drains can get blocked by the drainage fluid and material. For this reason, it is thought that flushing the chest drain with saline solution, can help maintain the patency of the tube. This proposed study will evaluate the impact of regular chest drain flushing on the length of time to chest tube removal and total hospitalization as well as improvement in chest imaging and the need for additional interventions on the infected space.
Primary Outcome
The investigators will assess the time from randomization (within 24 hours of chest tube placement) until time to chest tube removal
Conditions Studied
Interventions
- OTHER Saline Flush
Study Locations (5)
Michigan
- Henry Ford - Sterling Heights
Nebraska
- Creighton University - Omaha
New York
- Mount Sinai - New York
Tennessee
- Vanderbilt University Medical Center - Nashville
Virginia
- Virginia Commonwealth University - Richmond
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 96 participants |
| Start Date | 2024-06-21 |
| Est. Completion | 2026-12-30 |
| Phase | NA |
What NCT06427538 shows while recruiting
NCT06427538 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 96 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).
The record links to 2 conditions, with Pleural Infection appearing as the primary indexed condition, and to 1 intervention - of which Saline Flush is the first listed.
NCT06427538 lists 5 locations in 5 states (Michigan, Nebraska, New York).
Frequently Asked Questions
What is clinical trial NCT06427538 about?
NCT06427538 is a clinical study titled "Chest Drain Regular Flushing in Complicated Parapneumonic Effusions and Empyemas". Infections of the pleural space are common, and patients require antibiotics and chest drain placement to evacuate the chest from the infected fluid. Chest drains can get blocked by the drainage fluid and material. For this reason, it is thought that flushing the chest drain with saline solution, ca...
What is the current status of trial NCT06427538?
This trial is currently recruiting. It is a NA study. The enrollment target is 96 participants. The study started on 2024-06-21. Estimated completion is 2026-12-30.
What conditions does trial NCT06427538 study?
This clinical trial studies the following conditions: Pleural Infection, Empyema, Pleural.
What interventions are being tested in trial NCT06427538?
The interventions under investigation include: Saline Flush (OTHER).
Who is sponsoring clinical trial NCT06427538?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06427538 being conducted?
This trial has 5 study locations across Michigan, Nebraska, New York, Tennessee, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pleural Infection
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06427538's enrollment target sits among peer trials
96 925th of 2000 higher than 1,070 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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