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Chest Drain Regular Flushing in Complicated Parapneumonic Effusions and Empyemas
NCT06427538 · View on ClinicalTrials.gov ↗
Study Summary
Infections of the pleural space are common, and patients require antibiotics and chest drain placement to evacuate the chest from the infected fluid. Chest drains can get blocked by the drainage fluid and material. For this reason, it is thought that flushing the chest drain with saline solution, can help maintain the patency of the tube. This proposed study will evaluate the impact of regular chest drain flushing on the length of time to chest tube removal and total hospitalization as well as improvement in chest imaging and the need for additional interventions on the infected space.
Conditions Studied
Interventions
- OTHER Saline Flush
Study Locations (5)
Michigan
- Henry Ford — Sterling Heights
Nebraska
- Creighton University — Omaha
New York
- Mount Sinai — New York
Tennessee
- Vanderbilt University Medical Center — Nashville
Virginia
- Virginia Commonwealth University — Richmond
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 96 participants |
| Start Date | 2024-06-21 |
| Est. Completion | 2026-12-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06427538
The ClinicalTrials.gov registry entry for NCT06427538 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 96 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanderbilt University Medical Center, which has 695 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Pleural Infection appearing as the primary indexed condition, and to 1 intervention — of which Saline Flush is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06427538 reports 5 study locations spanning 5 distinct geographic areas — top geographies include Michigan, Nebraska, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06427538 about?
NCT06427538 is a clinical study titled "Chest Drain Regular Flushing in Complicated Parapneumonic Effusions and Empyemas". Infections of the pleural space are common, and patients require antibiotics and chest drain placement to evacuate the chest from the infected fluid. Chest drains can get blocked by the drainage fluid and material. For this reason, it is thought that flushing the chest drain with saline solution, ca...
What is the current status of trial NCT06427538?
This trial is currently recruiting. It is a NA study. The enrollment target is 96 participants. The study started on 2024-06-21. Estimated completion is 2026-12-30.
What conditions does trial NCT06427538 study?
This clinical trial studies the following conditions: Pleural Infection, Empyema, Pleural. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06427538?
The interventions under investigation include: Saline Flush (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06427538?
This trial is sponsored by Vanderbilt University Medical Center, which has 695 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06427538 being conducted?
This trial has 5 study locations across Michigan, Nebraska, New York, Tennessee, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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