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NCT06342414 · ClinicalTrials.gov registry record
An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer
A clinical trial of Hepatocellular Carcinoma and Cholangiocarcinoma, sponsored by City of Hope Medical Center.
- Recruiting
- Registry status
- 400
- Enrollment target
- 5
- Study locations
NCT06342414: Recruiting study of Hepatocellular Carcinoma and Cholangiocarcinoma, sponsored by City of Hope Medical Center.
NCT06342414 is a study of Hepatocellular Carcinoma and Cholangiocarcinoma that is actively recruiting participants, run by City of Hope Medical Center. The registered enrollment target is 400 participants, above the 255-participant average among 145 other Hepatocellular Carcinoma trials with a reported enrollment target (57% higher). The trial reports 5 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06342414, a study of Hepatocellular Carcinoma and Cholangiocarcinoma, is actively recruiting participants, sponsored by City of Hope Medical Center.
- RECRUITING
- Registry status
- 400 participants
- Enrollment target
- 5
- Study locations
Study Summary
It is sometimes difficult to precisely understand whether a primary liver cancer is a hepatocellular carcinoma or a cholangiocarcinoma. The researchers will develop and validate a liquid biopsy, based on exosomal content analysis and powered by machine learning, to help clinicians differentiate these two cancers before surgery.
Primary Outcome
True Positive Rate: the probability of a positive test result, conditioned on the individual truly being positive
Conditions Studied
Interventions
- DIAGNOSTIC_TEST ELUCIDATE
Study Locations (5)
Other
- Graduate School of Medical Sciences, Kyushu University - Fukuoka
- Graduate School of Medical Sciences, Kumamoto University - Kumamoto
- Hokkaido University Graduate School of Medicine - Sapporo
- Tokushima University - Tokushima
California
- City of Hope Medical Center - Duarte
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2024-03-15 |
| Est. Completion | 2026-06-18 |
What NCT06342414 shows while recruiting
NCT06342414 is an observational study that tracks outcomes without assigning an intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, above the 255-participant average among 145 other Hepatocellular Carcinoma trials with a reported enrollment target (57% higher).
The record links to 7 conditions, with Hepatocellular Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which ELUCIDATE is the first listed.
NCT06342414 lists 5 locations in 2 states (Other, California).
Frequently Asked Questions
What is clinical trial NCT06342414 about?
NCT06342414 is a clinical study titled "An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer". It is sometimes difficult to precisely understand whether a primary liver cancer is a hepatocellular carcinoma or a cholangiocarcinoma. The researchers will develop and validate a liquid biopsy, based on exosomal content analysis and powered by machine learning, to help clinicians differentiate thes...
What is the current status of trial NCT06342414?
This trial is currently recruiting. The enrollment target is 400 participants. The study started on 2024-03-15. Estimated completion is 2026-06-18.
What conditions does trial NCT06342414 study?
This clinical trial studies the following conditions: Hepatocellular Carcinoma, Cholangiocarcinoma, Intrahepatic Cholangiocarcinoma, Hepatic Cancer, Primary Liver Cancer.
What interventions are being tested in trial NCT06342414?
The interventions under investigation include: ELUCIDATE (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT06342414?
This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06342414 being conducted?
This trial has 5 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hepatocellular Carcinoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06342414's enrollment target sits among peer trials
400 31st of 145 higher than 115 of 145 other Hepatocellular Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hepatocellular Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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