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NCT06342414 · ClinicalTrials.gov registry record

An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

A clinical trial of Hepatocellular Carcinoma and Cholangiocarcinoma, sponsored by City of Hope Medical Center.

Recruiting
Registry status
400
Enrollment target
5
Study locations

NCT06342414 is a study of Hepatocellular Carcinoma and Cholangiocarcinoma that is actively recruiting participants, run by City of Hope Medical Center. The registered enrollment target is 400 participants, above the 255-participant average among 145 other Hepatocellular Carcinoma trials with a reported enrollment target (57% higher). The trial reports 5 study locations across 2 states.

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The verdict

NCT06342414, a study of Hepatocellular Carcinoma and Cholangiocarcinoma, is actively recruiting participants, sponsored by City of Hope Medical Center.

RECRUITING
Registry status
400 participants
Enrollment target
5
Study locations

Study Summary

It is sometimes difficult to precisely understand whether a primary liver cancer is a hepatocellular carcinoma or a cholangiocarcinoma. The researchers will develop and validate a liquid biopsy, based on exosomal content analysis and powered by machine learning, to help clinicians differentiate these two cancers before surgery.

Interventions

  • DIAGNOSTIC_TEST ELUCIDATE

Study Locations (5)

Other

  • Graduate School of Medical Sciences, Kyushu University - Fukuoka
  • Graduate School of Medical Sciences, Kumamoto University - Kumamoto
  • Hokkaido University Graduate School of Medicine - Sapporo
  • Tokushima University - Tokushima

California

  • City of Hope Medical Center - Duarte

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2024-03-15
Est. Completion 2026-06-18

Sponsor

City of Hope Medical Center

582 total trials

What the Registry Record Tells You About NCT06342414

The ClinicalTrials.gov registry entry for NCT06342414 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 255-participant average among 145 other Hepatocellular Carcinoma trials with a reported enrollment target (57% higher). The listed sponsor is City of Hope Medical Center, which has 582 total studies on file at ClinicalTrials.gov.

The record links to 7 conditions, with Hepatocellular Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which ELUCIDATE is the first listed.

NCT06342414 reports 5 study locations spanning 2 distinct geographic areas - top geographies include Other, California.

Frequently Asked Questions

What is clinical trial NCT06342414 about?

NCT06342414 is a clinical study titled "An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer". It is sometimes difficult to precisely understand whether a primary liver cancer is a hepatocellular carcinoma or a cholangiocarcinoma. The researchers will develop and validate a liquid biopsy, based on exosomal content analysis and powered by machine learning, to help clinicians differentiate thes...

What is the current status of trial NCT06342414?

This trial is currently recruiting. The enrollment target is 400 participants. The study started on 2024-03-15. Estimated completion is 2026-06-18.

What conditions does trial NCT06342414 study?

This clinical trial studies the following conditions: Hepatocellular Carcinoma, Cholangiocarcinoma, Intrahepatic Cholangiocarcinoma, Hepatic Cancer, Primary Liver Cancer.

What interventions are being tested in trial NCT06342414?

The interventions under investigation include: ELUCIDATE (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT06342414?

This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06342414 being conducted?

This trial has 5 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.