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NCT06335199 · ClinicalTrials.gov registry record · NA
tVNS Responsiveness Testing With Pupil Size
A NA study, sponsored by Georgia Institute of Technology.
- Completed
- Registry status
- NA
- Development phase
- 21
- Enrollment target
NCT06335199: Completed NA study, sponsored by Georgia Institute of Technology.
NCT06335199 is a NA study that has completed, run by Georgia Institute of Technology. The registered enrollment target is 21 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06335199, a NA study, has completed, sponsored by Georgia Institute of Technology.
- COMPLETED
- Registry status
- NA
- Development phase
- 21 participants
- Enrollment target
Study Summary
The goal of this study is to learn about the acute pupil response to transcutaneous vagus nerve stimulation (tVNS) in stroke survivors and healthy adults. The main question it aims to answer is whether pupil size response is greater with bilateral tVNS compared to unilateral tVNS. Participants will receive tVNS and sham at the outer ear unilaterally and bilaterally in resting condition. The pupil size of the participants will be recorded during tVNS.
Primary Outcome
Acute change in pupil size in response to electrical stimulation, relatively expressed as a percent change from the baseline
Interventions
- PROCEDURE Unilateral Left tVNS stimulation
- PROCEDURE Bilateral tVNS stimulation
- PROCEDURE Unilateral Left Sham stimulation
- PROCEDURE Bilateral Sham stimulation
- PROCEDURE Unilateral Right tVNS stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2024-11-14 |
| Est. Completion | 2025-10-27 |
| Phase | NA |
What the finished NCT06335199 record still lists
NCT06335199 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 5 interventions - of which Unilateral Left tVNS stimulation is the first listed.
NCT06335199 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06335199 about?
NCT06335199 is a clinical study titled "tVNS Responsiveness Testing With Pupil Size". The goal of this study is to learn about the acute pupil response to transcutaneous vagus nerve stimulation (tVNS) in stroke survivors and healthy adults. The main question it aims to answer is whether pupil size response is greater with bilateral tVNS compared to unilateral tVNS. Participants will ...
What is the current status of trial NCT06335199?
This trial is currently completed. It is a NA study. The enrollment target is 21 participants. The study started on 2024-11-14. Estimated completion is 2025-10-27.
What interventions are being tested in trial NCT06335199?
The interventions under investigation include: Unilateral Left tVNS stimulation (PROCEDURE), Bilateral tVNS stimulation (PROCEDURE), Unilateral Left Sham stimulation (PROCEDURE), Bilateral Sham stimulation (PROCEDURE), Unilateral Right tVNS stimulation (PROCEDURE).
Who is sponsoring clinical trial NCT06335199?
This trial is sponsored by Georgia Institute of Technology, which has 24 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06335199's enrollment target sits among peer trials
21 1762nd of 2000 higher than 233 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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