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NCT06289010 · ClinicalTrials.gov registry record · NA
Neural Mechanisms of Family-Focused Treatment for Youth Depression
A NA study of Childhood Depression, sponsored by Boston University Charles River Campus.
- Recruiting
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 2
- Study locations
NCT06289010: Recruiting NA study of Childhood Depression, sponsored by Boston University Charles River Campus.
NCT06289010 is a NA study of Childhood Depression that is actively recruiting participants, run by Boston University Charles River Campus. The registered enrollment target is 80 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06289010, a NA study of Childhood Depression, is actively recruiting participants, sponsored by Boston University Charles River Campus.
- RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 2
- Study locations
Study Summary
The goal of this interventional study is to compare the baseline neural mechanisms and parenting in depressed and non-depressed children and to examine baseline neural mechanisms and parenting as predictors of Family-Focused Treatment for Childhood-Depression (FFT-CD) outcomes. The main questions it aims to answer are: * What are differences between depressed and non-depressed participants on baseline neural and parenting indicators? * Do baseline neural and parenting indicators predict response to FFT-CD? * Does change in parenting and neural functioning mediate change in depression from baseline to follow-up? Participants will: * complete baseline clinical measures * complete neuroimaging tasks via Functional Magnetic Resonance Imaging (fMR) * undergo a 12-session course of FFT-CD * complete follow up evaluations and neuroimaging
Primary Outcome
\>/= 50% reduction on Children's Depression Rating Scale-Revised (CDRS-R). Scores on this measure range from 17 to 113, and higher scores indicate greater depression severity.
Conditions Studied
Interventions
- BEHAVIORAL Family-Focused Treatment for Childhood-Depression (FFT-CD)
Study Locations (2)
Massachusetts
- Boston University - Boston
- Athinoula A. Martinos Imaging Center at Massachusetts Institute of Technology - Charlestown
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2024-08-20 |
| Est. Completion | 2027-11 |
| Phase | NA |
What NCT06289010 shows while recruiting
NCT06289010 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Childhood Depression appearing as the primary indexed condition, and to 1 intervention - of which Family-Focused Treatment for Childhood-Depression (FFT-CD) is the first listed.
NCT06289010 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06289010 about?
NCT06289010 is a clinical study titled "Neural Mechanisms of Family-Focused Treatment for Youth Depression". The goal of this interventional study is to compare the baseline neural mechanisms and parenting in depressed and non-depressed children and to examine baseline neural mechanisms and parenting as predictors of Family-Focused Treatment for Childhood-Depression (FFT-CD) outcomes. The main questions it...
What is the current status of trial NCT06289010?
This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2024-08-20. Estimated completion is 2027-11.
What conditions does trial NCT06289010 study?
This clinical trial studies the following conditions: Childhood Depression.
What interventions are being tested in trial NCT06289010?
The interventions under investigation include: Family-Focused Treatment for Childhood-Depression (FFT-CD) (BEHAVIORAL).
Who is sponsoring clinical trial NCT06289010?
This trial is sponsored by Boston University Charles River Campus, which has 104 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06289010 being conducted?
This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Childhood Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06289010's enrollment target sits among peer trials
80 994th of 2000 higher than 941 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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