Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06215014 · ClinicalTrials.gov registry record · NA
Sex Effects on Blood Pressure With Handgrip Training
A NA study of Blood Pressure, sponsored by University of Massachusetts, Boston.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 2
- Study locations
NCT06215014: Recruiting NA study of Blood Pressure, sponsored by University of Massachusetts, Boston.
NCT06215014 is a NA study of Blood Pressure that is actively recruiting participants, run by University of Massachusetts, Boston. The registered enrollment target is 50 participants, below the 286-participant average among 101 other Blood Pressure trials with a reported enrollment target (83% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06215014, a NA study of Blood Pressure, is actively recruiting participants, sponsored by University of Massachusetts, Boston.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 2
- Study locations
Study Summary
The goal of this intervention is to compare the blood pressure response of young females and males to a single bout of static handgrip exercise before and after static handgrip training (4 weeks). The main questions this study aims to answer are: * Are the lowering blood pressure effects of static handgrip exercise training different between young females and males? * Which factors explain the lowering blood pressure effects of static handgrip training and possible differences between sexes? Is it an improved blood vessel dilation? Is it a reduced stiffening of blood vessels? Is it a reduced fight or flight response resulting in a lower heart rate and blood pumped by the heart into the vessels? All the above? * Which factors regulate blood pressure response during and immediately after a single bout of static handgrip exercise? All participants will be asked to: * Visit the laboratory to perform static handgrip exercise - first visit; * Participants will be randomized (like flipping a coin) to static handgrip exercise training or to a non-exercising phase, with each phase lasting four weeks. Participants will also complete the other condition (handgrip or no handgrip) after completing the first four-week condition * Return to the laboratory after the completion of both static handgrip training and no training to perform the static handgrip exercise of the first visit. The investigators will compare participants' blood pressure response to a single bout static of handgrip exercise after training to their own blood pressure response to the same bout of exercise after the non-training period.
Primary Outcome
Systolic and diastolic blood pressure
Conditions Studied
Interventions
- OTHER Isometric handgrip training
Study Locations (2)
Massachusetts
- UMassachusetts Boston - Boston
- University of Massachusetts Boston - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2024-03-01 |
| Est. Completion | 2025-10 |
| Phase | NA |
What NCT06215014 shows while recruiting
NCT06215014 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 286-participant average among 101 other Blood Pressure trials with a reported enrollment target (83% lower).
The record links to 1 condition, with Blood Pressure appearing as the primary indexed condition, and to 1 intervention - of which Isometric handgrip training is the first listed.
NCT06215014 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06215014 about?
NCT06215014 is a clinical study titled "Sex Effects on Blood Pressure With Handgrip Training". The goal of this intervention is to compare the blood pressure response of young females and males to a single bout of static handgrip exercise before and after static handgrip training (4 weeks). The main questions this study aims to answer are: * Are the lowering blood pressure effects of static...
What is the current status of trial NCT06215014?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2024-03-01. Estimated completion is 2025-10.
What conditions does trial NCT06215014 study?
This clinical trial studies the following conditions: Blood Pressure.
What interventions are being tested in trial NCT06215014?
The interventions under investigation include: Isometric handgrip training (OTHER).
Who is sponsoring clinical trial NCT06215014?
This trial is sponsored by University of Massachusetts, Boston, which has 18 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06215014 being conducted?
This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Blood Pressure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06215014's enrollment target sits among peer trials
50 57th of 101 higher than 41 of 101 other Blood Pressure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Blood Pressure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Ketone Ester And Salt (KEAS) in Older Adults
RECRUITING · NA
-
Cocooned Moms Study
RECRUITING · NA
-
The GUARDIAN Trial
RECRUITING · NA
-
The Venous Distension Reflex and Orthostatic Hypertension
RECRUITING · NA
-
Breaking up Prolonged Sedentary Behavior to Improve Cardiometabolic Health
RECRUITING · NA
-
The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00200889 · 50 participants · Early Phase 1
Mapping Auricular Vagus Nerve Circuitry
- NCT00409435 · 50 participants · Phase 2
A Study of Pyridostigmine in Postural Tachycardia Syndrome
- NCT01202305 · 50 participants
The Use of Lymph Node Biopsies to Support HIV Pathogenesis Studies
- NCT01225913 · 50 participants · Phase 4
Mechanism(s) of Airflow Limitation During Exacerbation of Asthma
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI