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NCT06160284 · ClinicalTrials.gov registry record · Phase 1

Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)

A Phase 1 study of Opioid Use Disorder, sponsored by Yale University.

Recruiting
Registry status
Phase 1
Development phase
12
Enrollment target
1
Study location

NCT06160284 is a Phase 1 study of Opioid Use Disorder that is actively recruiting participants, run by Yale University. The registered enrollment target is 12 participants, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06160284, a Phase 1 study of Opioid Use Disorder, is actively recruiting participants, sponsored by Yale University.

RECRUITING
Registry status
Phase 1
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

This study will examine the synaptotrophic effects of psilocybin among medically healthy, detoxified OUD subjects. Eligible OUD participants will undergo pre- and post- psilocybin administration PET scans with the \[11C\]-UCB-J radiotracer while inpatient.

Conditions Studied

Opioid Use Disorder

Interventions

  • DRUG Psilocybin

Study Locations (1)

Connecticut

  • Yale University - New Haven

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2025-05-28
Est. Completion 2027-01
Phase Phase 1

Sponsor

Yale University

1,492 total trials

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What the Registry Record Tells You About NCT06160284

The ClinicalTrials.gov registry entry for NCT06160284 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (100% lower). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Opioid Use Disorder appearing as the primary indexed condition, and to 1 intervention - of which Psilocybin is the first listed.

NCT06160284 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.

Frequently Asked Questions

What is clinical trial NCT06160284 about?

NCT06160284 is a clinical study titled "Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)". This study will examine the synaptotrophic effects of psilocybin among medically healthy, detoxified OUD subjects. Eligible OUD participants will undergo pre- and post- psilocybin administration PET scans with the \[11C\]-UCB-J radiotracer while inpatient.

What is the current status of trial NCT06160284?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2025-05-28. Estimated completion is 2027-01.

What conditions does trial NCT06160284 study?

This clinical trial studies the following conditions: Opioid Use Disorder.

What interventions are being tested in trial NCT06160284?

The interventions under investigation include: Psilocybin (DRUG).

Who is sponsoring clinical trial NCT06160284?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06160284 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.