Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06143293 · ClinicalTrials.gov registry record · NA
Research Evaluating Vagal Excitation AND Anatomical Links
A NA study of Epilepsy and Depressive Disorder, sponsored by University of Minnesota.
- Recruiting
- Registry status
- NA
- Development phase
- 144
- Enrollment target
- 1
- Study location
NCT06143293 is a NA study of Epilepsy and Depressive Disorder that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 144 participants, below the 952-participant average among 160 other Epilepsy trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06143293, a NA study of Epilepsy and Depressive Disorder, is actively recruiting participants, sponsored by University of Minnesota.
- RECRUITING
- Registry status
- NA
- Development phase
- 144 participants
- Enrollment target
- 1
- Study location
Study Summary
The acute and chronic effects of VNS stimulation on various on the autonomic nervous, cardiovascular, immune, and metabolic systems will be compared from noninvasive and minimally invasive physiological recordings and blood draws at various time points throughout the study. These interventions and assessments will be performed in individuals 18 years of age and older who are implanted with a VNS device, which consists of patients who have been diagnosed with drug resistant epilepsy or major depressive disorder. The REVEAL study is not a treatment study; its primary objective is to scientifically investigate the contributing roles of efferent versus afferent vagus nerve modulation of multiple peripheral organs and their dependence on stimulation parameters, in which participants are those who have been implanted with a VNS device be receive standard of care treatment for their epilepsy or depressive disorder.
Conditions Studied
Interventions
- DEVICE Vagus nerve stimulation device: acute and chronic administration of investigational vagus nerve stimulation parameters
Study Locations (1)
Minnesota
- University of Minnesota - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 144 participants |
| Start Date | 2023-12-15 |
| Est. Completion | 2026-08-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06143293
The ClinicalTrials.gov registry entry for NCT06143293 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 144 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 952-participant average among 160 other Epilepsy trials with a reported enrollment target (85% lower). The listed sponsor is University of Minnesota, which has 966 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Epilepsy appearing as the primary indexed condition, and to 1 intervention - of which Vagus nerve stimulation device: acute and chronic administration of investigational vagus nerve stimulation parameters is the first listed.
NCT06143293 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.
Frequently Asked Questions
What is clinical trial NCT06143293 about?
NCT06143293 is a clinical study titled "Research Evaluating Vagal Excitation AND Anatomical Links". The acute and chronic effects of VNS stimulation on various on the autonomic nervous, cardiovascular, immune, and metabolic systems will be compared from noninvasive and minimally invasive physiological recordings and blood draws at various time points throughout the study. These interventions and a...
What is the current status of trial NCT06143293?
This trial is currently recruiting. It is a NA study. The enrollment target is 144 participants. The study started on 2023-12-15. Estimated completion is 2026-08-31.
What conditions does trial NCT06143293 study?
This clinical trial studies the following conditions: Epilepsy, Depressive Disorder.
What interventions are being tested in trial NCT06143293?
The interventions under investigation include: Vagus nerve stimulation device: acute and chronic administration of investigational vagus nerve stimulation parameters (DEVICE).
Who is sponsoring clinical trial NCT06143293?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06143293 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Epilepsy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
SeizEAR Safety Study
RECRUITING · NA
-
Understanding Prefrontal and Medial Temporal Neuronal Responses to Algorithmic Cognitive Variables in Epilepsy Patients
RECRUITING · NA
-
Subcortical Arousal in Perceptual Awareness
RECRUITING · NA
-
Prediction of Anxiety and Memory State
RECRUITING · NA
-
Implementation and Cost Evaluation of Project UPLIFT
RECRUITING · NA
-
Amygdala Memory Enhancement
RECRUITING · NA
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.