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NCT06132893 · ClinicalTrials.gov registry record · Phase 2
A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
A Phase 2 study of Focal Epilepsy, sponsored by Biohaven Therapeutics.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 390
- Enrollment target
- 20
- Study locations
NCT06132893: Recruiting Phase 2 study of Focal Epilepsy, sponsored by Biohaven Therapeutics.
NCT06132893 is a Phase 2 study of Focal Epilepsy that is actively recruiting participants, run by Biohaven Therapeutics. The registered enrollment target is 390 participants, above the 123-participant average among 8 other Focal Epilepsy trials with a reported enrollment target (217% higher). The trial reports 20 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06132893, a Phase 2 study of Focal Epilepsy, is actively recruiting participants, sponsored by Biohaven Therapeutics.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 390 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to determine whether BHV-7000 is effective in the treatment of refractory focal epilepsy.
Primary Outcome
To compare the efficacy of each of 2 doses of BHV-7000 to placebo as an adjunctive therapy for refractory focal onset epilepsy as measured by the change from OP (observational phase) in 28-day average seizure frequency. The primary objective will be measured by comparing the observation phase (8 weeks) to the 12-week double-blind treatment phase.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG BHV-7000
Study Locations (20)
Florida
- EZR Research LLC - Boca Raton
- Nova Clinical Research, LLC - Bradenton
- University of Florida (Jacksonville) - Jacksonville
- University of Miami - Miami
- Floridian Research Institute - Miami
- AdventHealth Orlando - Orlando
- Medsol Clinical Research Center - Port Charlotte
- Santos Research Center - Tampa
- Encore Medical Research of Weston LLC. - Weston
- Pediatrix Medical Group of Florida - Winter Park
California
- University of California San Diego - La Jolla
- University of California, Los Angeles - Los Angeles
- Stanford Health Care - Palo Alto
- Profound Research LLC - Pasadena
Arizona
- Barrow Neurological Institute - Phoenix
- Center for Neurosciences - Tucson
Arkansas
- Clinical Trials, Inc. - Little Rock
- WRN - Rogers
Colorado
- University of Colorado Anschultz Medical Campus - Aurora
Connecticut
- Yale School of Medicine - Yale-New Haven Hospital - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 390 participants |
| Start Date | 2024-03-14 |
| Est. Completion | 2026-12 |
| Phase | Phase 2 |
What NCT06132893 shows while recruiting
NCT06132893 is an interventional study that assigns participants to a tested intervention. The registered 390 participants enrollment target is mid-sized for trials with a published cap, above the 123-participant average among 8 other Focal Epilepsy trials with a reported enrollment target (217% higher).
The record links to 1 condition, with Focal Epilepsy appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06132893 names 20 study sites across 6 states, led by Florida, California, Arizona.
Frequently Asked Questions
What is clinical trial NCT06132893 about?
NCT06132893 is a clinical study titled "A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy". The purpose of this study is to determine whether BHV-7000 is effective in the treatment of refractory focal epilepsy.
What is the current status of trial NCT06132893?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 390 participants. The study started on 2024-03-14. Estimated completion is 2026-12.
What conditions does trial NCT06132893 study?
This clinical trial studies the following conditions: Focal Epilepsy.
What interventions are being tested in trial NCT06132893?
The interventions under investigation include: Placebo (DRUG), BHV-7000 (DRUG).
Who is sponsoring clinical trial NCT06132893?
This trial is sponsored by Biohaven Therapeutics, which has 16 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06132893 being conducted?
This trial has 20 study locations across Arizona, Arkansas, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Focal Epilepsy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06132893's enrollment target sits among peer trials
390 1st of 8 the highest of 8 other Focal Epilepsy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Focal Epilepsy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
RECRUITING · Phase 2
-
A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures
RECRUITING · Phase 2
-
A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy
ACTIVE NOT RECRUITING · Phase 2
-
Diffusion MRI Methods to Minimize Postoperative Deficits in Pediatric Epilepsy Surgery
RECRUITING · NA
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Breathing Rescue for SUDEP Prevention
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-
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