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RECRUITING Phase 2

A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures

NCT07219407 · View on ClinicalTrials.gov ↗

Study Summary

This is a clinical research study for an investigational drug called RAP-219 in patients with Refractory Focal Epilepsy. This study is being conducted to determine RAP-219 Long- term safety and open-label antiseizure activity in patients with Refractory Focal Epilepsy.

Interventions

  • DRUG RAP-219

Study Locations (7)

Idaho

  • Consultants in Epilepsy and Neurology, PLLC — Boise

Minnesota

  • Mayo Clinic — Rochester

New York

  • NYU Langone Comprehensive Epilepsy Center — New York

Ohio

  • Cleveland Clinic Foundation — Cleveland

Pennsylvania

  • University of Pennsylvania - Department of Neurology — Philadelphia

Tennessee

  • Vanderbilt University Medical Center — Nashville

Texas

  • Baylor College of Medicine — Houston

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-12-15
Est. Completion 2028-02-03
Phase Phase 2

Sponsor

Rapport Therapeutics

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07219407

The ClinicalTrials.gov registry entry for NCT07219407 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Rapport Therapeutics, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 6 conditions, with Epilepsy appearing as the primary indexed condition, and to 1 intervention — of which RAP-219 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07219407 reports 7 study locations spanning 7 distinct geographic areas — top geographies include Idaho, Minnesota, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07219407 about?

NCT07219407 is a clinical study titled "A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures". This is a clinical research study for an investigational drug called RAP-219 in patients with Refractory Focal Epilepsy. This study is being conducted to determine RAP-219 Long- term safety and open-label antiseizure activity in patients with Refractory Focal Epilepsy.

What is the current status of trial NCT07219407?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2025-12-15. Estimated completion is 2028-02-03.

What conditions does trial NCT07219407 study?

This clinical trial studies the following conditions: Epilepsy, Focal Epilepsy, Seizure, Focal Seizure, Focal Onset Seizure. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07219407?

The interventions under investigation include: RAP-219 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07219407?

This trial is sponsored by Rapport Therapeutics, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07219407 being conducted?

This trial has 7 study locations across Idaho, Minnesota, New York, Ohio, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial