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NCT06127147 · ClinicalTrials.gov registry record · NA
High-intensity Inspiratory Muscle Training as a Pre-cardiac Rehabilitation in Heart Disease
A NA study of Coronary Artery Bypass Graft and CABG, sponsored by University of Illinois at Chicago.
- Completed
- Registry status
- NA
- Development phase
- 11
- Enrollment target
- 2
- Study locations
NCT06127147 is a NA study of Coronary Artery Bypass Graft and CABG that has completed, run by University of Illinois at Chicago. The registered enrollment target is 11 participants. The trial reports 2 study locations across 1 state.
The verdict
NCT06127147, a NA study of Coronary Artery Bypass Graft and CABG, has completed, sponsored by University of Illinois at Chicago.
- COMPLETED
- Registry status
- NA
- Development phase
- 11 participants
- Enrollment target
- 2
- Study locations
Study Summary
Background/aim: Endothelial function is closely associated with coronary artery health among individuals being treated for heart disease. An impairment in endothelial function promotes arterial stiffening that directly contributes to elevated systolic blood pressure as a result of increased vascular resistance. Inspiratory muscle training is simply a form of training consisting of repeated inspirations against resistance. Inspiratory muscle training has also been applied to patients with chronic disease or as an additional therapy for cardiac rehabilitation and it has proven to be safe in these groups. Few studies in the literature examined the effects of high-intensity inspiratory muscle training in this population, however, these studies did not examine the direct effects of inspiratory muscle training on vascular function. To the best of our knowledge, the effects of inspiratory muscle training in patients with heart disease on endothelial function and arterial stiffness prior to starting cardiac rehabilitation have not been investigated. This study aims to investigate and interpret whether high-intensity inspiratory muscle training, beyond the usual care of heart disease, improves endothelial function and arterial stiffness. Methods: The study was designed as a randomized controlled trial. Patients will be allocated for inspiratory muscle training (IMT) with 60% of maximum inspiratory pressure (MIP) or sham inspiratory muscle training (Sham-control), for 4 weeks. In both groups, before and after 4-week training, cardiovascular functions will be measured and compared.
Conditions Studied
Interventions
- DEVICE IMT
- DEVICE Sham-IMT
Study Locations (2)
Illinois
- University of Illinois at Chicago - Chicago
- University of Illinois Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2023-12-20 |
| Est. Completion | 2024-06-15 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06127147
The ClinicalTrials.gov registry entry for NCT06127147 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 11 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Illinois at Chicago, which has 430 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Coronary Artery Bypass Graft appearing as the primary indexed condition, and to 2 interventions - of which IMT is the first listed.
NCT06127147 reports 2 study locations spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT06127147 about?
NCT06127147 is a clinical study titled "High-intensity Inspiratory Muscle Training as a Pre-cardiac Rehabilitation in Heart Disease". Background/aim: Endothelial function is closely associated with coronary artery health among individuals being treated for heart disease. An impairment in endothelial function promotes arterial stiffening that directly contributes to elevated systolic blood pressure as a result of increased vascular...
What is the current status of trial NCT06127147?
This trial is currently completed. It is a NA study. The enrollment target is 11 participants. The study started on 2023-12-20. Estimated completion is 2024-06-15.
What conditions does trial NCT06127147 study?
This clinical trial studies the following conditions: Coronary Artery Bypass Graft, CABG.
What interventions are being tested in trial NCT06127147?
The interventions under investigation include: IMT (DEVICE), Sham-IMT (DEVICE).
Who is sponsoring clinical trial NCT06127147?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06127147 being conducted?
This trial has 2 study locations across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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