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NCT06110494 · ClinicalTrials.gov registry record · Phase 4
A New Clinical Use of Ferumoxytol Nanoparticles: An Antibiofilm Treatment
A Phase 4 study of Apical Periodontitis and Pulp Disease, Dental, sponsored by University of Pennsylvania.
- Completed
- Registry status
- Phase 4
- Development phase
- 44
- Enrollment target
- 1
- Study location
NCT06110494 is a Phase 4 study of Apical Periodontitis and Pulp Disease, Dental that has completed, run by University of Pennsylvania. The registered enrollment target is 44 participants, below the 67-participant average among 4 other Apical Periodontitis trials with a reported enrollment target (34% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06110494, a Phase 4 study of Apical Periodontitis and Pulp Disease, Dental, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 44 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this observational is study is to develop a protocol for root canal biofilms disinfection using a clinically approved and commercially available iron oxide nanoparticle formulation Ferumoxytol/H2O2 treatments. This protocol will be testing local single topical application of Ferumoxytol within the root canal system in patients going through routine root canal treatment, evaluate its potential as anti-biofilm treatment and compare it to the clinical gold standard disinfecting solution sodium hypochlorite (positive control) and saline (negative control).
Conditions Studied
Interventions
- DRUG Iron oxide nanoparticles treatment Ferumoxytol/H2O2
- DRUG NaOCl
- DRUG NaCl
- DRUG supplementary irrigation
Study Locations (1)
Pennsylvania
- University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2020-07-13 |
| Est. Completion | 2022-03-10 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06110494
The ClinicalTrials.gov registry entry for NCT06110494 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 44 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 67-participant average among 4 other Apical Periodontitis trials with a reported enrollment target (34% lower). The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Apical Periodontitis appearing as the primary indexed condition, and to 4 interventions - of which Iron oxide nanoparticles treatment Ferumoxytol/H2O2 is the first listed.
NCT06110494 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06110494 about?
NCT06110494 is a clinical study titled "A New Clinical Use of Ferumoxytol Nanoparticles: An Antibiofilm Treatment". The goal of this observational is study is to develop a protocol for root canal biofilms disinfection using a clinically approved and commercially available iron oxide nanoparticle formulation Ferumoxytol/H2O2 treatments. This protocol will be testing local single topical application of Ferumoxytol ...
What is the current status of trial NCT06110494?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 44 participants. The study started on 2020-07-13. Estimated completion is 2022-03-10.
What conditions does trial NCT06110494 study?
This clinical trial studies the following conditions: Apical Periodontitis, Pulp Disease, Dental.
What interventions are being tested in trial NCT06110494?
The interventions under investigation include: Iron oxide nanoparticles treatment Ferumoxytol/H2O2 (DRUG), NaOCl (DRUG), NaCl (DRUG), supplementary irrigation (DRUG).
Who is sponsoring clinical trial NCT06110494?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06110494 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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