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NCT06843525 · ClinicalTrials.gov registry record
Bite Force Measurements
A clinical trial of Apical Periodontitis and Irreversible Pulpitis, sponsored by Rutgers, The State University of New Jersey.
- Recruiting
- Registry status
- 112
- Enrollment target
- 1
- Study location
NCT06843525: Recruiting study of Apical Periodontitis and Irreversible Pulpitis, sponsored by Rutgers, The State University of New Jersey.
NCT06843525 is a study of Apical Periodontitis and Irreversible Pulpitis that is actively recruiting participants, run by Rutgers, The State University of New Jersey. The registered enrollment target is 112 participants, above the 50-participant average among 4 other Apical Periodontitis trials with a reported enrollment target (124% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06843525, a study of Apical Periodontitis and Irreversible Pulpitis, is actively recruiting participants, sponsored by Rutgers, The State University of New Jersey.
- RECRUITING
- Registry status
- 112 participants
- Enrollment target
- 1
- Study location
Study Summary
ABSTRACT: Acute dental pain from untreated decay often drives patients to emergency rooms (ERs), where the lack of definitive dental treatment results in nearly 75% of these patients receiving analgesics, predominantly opioids. Addressing the need for non-opioid pain alternatives is crucial. Emerging evidence suggests that dental pain from pulpal and periodontal conditions (affecting the tooth's nerve and surrounding tissues) involves neuropathic mechanisms, such as mechanical allodynia (MA) and central sensitization (CS). These mechanisms can amplify pain perception, causing typically non-painful actions, like chewing, to become painful and resulting in hypersensitivity extending beyond the affected tooth. Reliably identifying these mechanisms with quantitative measures can support improved pain assessment and targeted non-opioid treatment. This minimally invasive prospective cohort study will use the FDA-approved Innobyte® device, a precise bite-force measurement tool, to evaluate periodontal health and to quantify mechanical pain thresholds in patients requiring endodontic treatment (root canal therapy).
Primary Outcome
Ipsilateral full arch and tooth specific bite-force
Conditions Studied
Study Locations (1)
New Jersey
- Rutgers School of Dental Medicine - Newark
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 112 participants |
| Start Date | 2025-05-16 |
| Est. Completion | 2026-11-01 |
What NCT06843525 shows while recruiting
NCT06843525 is an observational study that tracks outcomes without assigning an intervention. The registered 112 participants enrollment target is mid-sized for trials with a published cap, above the 50-participant average among 4 other Apical Periodontitis trials with a reported enrollment target (124% higher).
The record links to 3 conditions, with Apical Periodontitis appearing as the primary indexed condition, and to 0 interventions.
NCT06843525 reports a single indexed study location in New Jersey.
Frequently Asked Questions
What is clinical trial NCT06843525 about?
NCT06843525 is a clinical study titled "Bite Force Measurements". ABSTRACT: Acute dental pain from untreated decay often drives patients to emergency rooms (ERs), where the lack of definitive dental treatment results in nearly 75% of these patients receiving analgesics, predominantly opioids. Addressing the need for non-opioid pain alternatives is crucial. Emergin...
What is the current status of trial NCT06843525?
This trial is currently recruiting. The enrollment target is 112 participants. The study started on 2025-05-16. Estimated completion is 2026-11-01.
What conditions does trial NCT06843525 study?
This clinical trial studies the following conditions: Apical Periodontitis, Irreversible Pulpitis, Pulpal Necrosis.
Who is sponsoring clinical trial NCT06843525?
This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06843525 being conducted?
This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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