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NCT06021626 · ClinicalTrials.gov registry record · Phase 1
A Study of CRD3874-SI in People With Solid Tumors
A Phase 1 study of Sarcoma and Merkel Cell Carcinoma, sponsored by Memorial Sloan Kettering Cancer Center.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 72
- Enrollment target
- 7
- Study locations
NCT06021626: Recruiting Phase 1 study of Sarcoma and Merkel Cell Carcinoma, sponsored by Memorial Sloan Kettering Cancer Center.
NCT06021626 is a Phase 1 study of Sarcoma and Merkel Cell Carcinoma that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 72 participants, below the 921-participant average among 122 other Sarcoma trials with a reported enrollment target (92% lower). The trial reports 7 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06021626, a Phase 1 study of Sarcoma and Merkel Cell Carcinoma, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 72 participants
- Enrollment target
- 7
- Study locations
Study Summary
This study will test the safety of a study drug called CRD3874-SI. The researchers will test different doses of CRD3874-SI to find the highest dose that causes few or mild side effects in participants. After the researchers find the highest safe dose of CRD3874-SI, they will test that dose in new groups of participants to help them learn more about the side effects of the study drug and find out whether CRD3874-SI is an effective treatment for for patients with advanced or metastatic malignant solid tumors including sarcoma and Merkel Cell Carcinoma.
Primary Outcome
The MTD is defined as the highest dose level studied at which \<2 subjects out of 6 experience a DLT. A dose level under consideration as the MTD will be expanded to six patients if only three have been accrued.
Conditions Studied
Interventions
- DRUG CRD3874
Study Locations (7)
New York
- Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities) - Commack
- Memorial Sloan Kettering Westchester (Limited Protocol Activities) - Harrison
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) - New York
- Memorial Sloan Kettering Nassau (Limited Protocol Activities) - Rockville Centre
New Jersey
- Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities) - Basking Ridge
- Memorial Sloan Kettering Monmouth (Limited Protocol Activities) - Middletown
- Memorial Sloan Kettering Bergen (Limited Protocol Activities) - Montvale
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2023-08-25 |
| Est. Completion | 2029-08 |
| Phase | Phase 1 |
What NCT06021626 shows while recruiting
NCT06021626 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, below the 921-participant average among 122 other Sarcoma trials with a reported enrollment target (92% lower).
The record links to 2 conditions, with Sarcoma appearing as the primary indexed condition, and to 1 intervention - of which CRD3874 is the first listed.
NCT06021626 lists 7 locations in 2 states (New York, New Jersey).
Frequently Asked Questions
What is clinical trial NCT06021626 about?
NCT06021626 is a clinical study titled "A Study of CRD3874-SI in People With Solid Tumors". This study will test the safety of a study drug called CRD3874-SI. The researchers will test different doses of CRD3874-SI to find the highest dose that causes few or mild side effects in participants. After the researchers find the highest safe dose of CRD3874-SI, they will test that dose in new gr...
What is the current status of trial NCT06021626?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 72 participants. The study started on 2023-08-25. Estimated completion is 2029-08.
What conditions does trial NCT06021626 study?
This clinical trial studies the following conditions: Sarcoma, Merkel Cell Carcinoma.
What interventions are being tested in trial NCT06021626?
The interventions under investigation include: CRD3874 (DRUG).
Who is sponsoring clinical trial NCT06021626?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06021626 being conducted?
This trial has 7 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sarcoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06021626's enrollment target sits among peer trials
72 52nd of 122 higher than 70 of 122 other Sarcoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sarcoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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