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NCT05996900 · ClinicalTrials.gov registry record · NA
Investigating the Neural Mechanisms of Repetitive Brain Stimulation With Invasive and Noninvasive Electrophysiology in Humans
A NA study of Major Depressive Disorder and Epilepsy, sponsored by Stanford University.
- Recruiting
- Registry status
- NA
- Development phase
- 49
- Enrollment target
- 1
- Study location
NCT05996900 is a NA study of Major Depressive Disorder and Epilepsy that is actively recruiting participants, run by Stanford University. The registered enrollment target is 49 participants, below the 377-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05996900, a NA study of Major Depressive Disorder and Epilepsy, is actively recruiting participants, sponsored by Stanford University.
- RECRUITING
- Registry status
- NA
- Development phase
- 49 participants
- Enrollment target
- 1
- Study location
Study Summary
Transcranial magnetic stimulation (TMS) is an effective treatment for depression, but clinical outcome is suboptimal, partially because investigators are missing biologically-grounded brain markers which show that TMS is modifying activity at the intended target in the brain. The goal of this proposal is to characterize the key markers of the brain's response to repeated doses of TMS with high resolution using invasive brain recordings in humans, and relate these brain markers to noninvasive recordings. These markers will improve the understanding of TMS and can be used to optimize and enhance clinical efficacy for depression and other psychiatric disorders.
Conditions Studied
Interventions
- DEVICE TMS
- DEVICE Intracranial electrodes
Study Locations (1)
California
- Stanford University - Stanford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 49 participants |
| Start Date | 2023-09-01 |
| Est. Completion | 2027-12-01 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05996900
The ClinicalTrials.gov registry entry for NCT05996900 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 49 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 377-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (87% lower). The listed sponsor is Stanford University, which has 1,744 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Major Depressive Disorder appearing as the primary indexed condition, and to 2 interventions - of which TMS is the first listed.
NCT05996900 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT05996900 about?
NCT05996900 is a clinical study titled "Investigating the Neural Mechanisms of Repetitive Brain Stimulation With Invasive and Noninvasive Electrophysiology in Humans". Transcranial magnetic stimulation (TMS) is an effective treatment for depression, but clinical outcome is suboptimal, partially because investigators are missing biologically-grounded brain markers which show that TMS is modifying activity at the intended target in the brain. The goal of this propos...
What is the current status of trial NCT05996900?
This trial is currently recruiting. It is a NA study. The enrollment target is 49 participants. The study started on 2023-09-01. Estimated completion is 2027-12-01.
What conditions does trial NCT05996900 study?
This clinical trial studies the following conditions: Major Depressive Disorder, Epilepsy.
What interventions are being tested in trial NCT05996900?
The interventions under investigation include: TMS (DEVICE), Intracranial electrodes (DEVICE).
Who is sponsoring clinical trial NCT05996900?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05996900 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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