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NCT05978804 · ClinicalTrials.gov registry record · NA
Home-based tDCS in Frontotemporal Dementia or Alzheimer's Disease
A NA study, sponsored by Johns Hopkins University.
- Terminated
- Registry status
- NA
- Development phase
- 36
- Enrollment target
NCT05978804: Clinical Trial NA study, sponsored by Johns Hopkins University.
NCT05978804 is a NA study that was terminated before completion, run by Johns Hopkins University. The registered enrollment target is 36 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05978804, a NA study, was terminated before completion, sponsored by Johns Hopkins University.
- TERMINATED
- Registry status
- NA
- Development phase
- 36 participants
- Enrollment target
Study Summary
The primary objective of this research is to evaluate the effects of non-invasive brain stimulation and computerized cognitive training on executive functioning in individuals with Primary Progressive Aphasia (PPA), mild cognitive impairment (MCI), or dementia. In this study, investigators will use transcranial direct current stimulation (tDCS) to stimulate the left dorsolateral prefrontal cortex (DLPFC). Previous studies have demonstrated that tDCS over the DLPFC led to improvements in attention deficit caused by stroke, Parkinson's Disease, and major depression as well as language deficits caused by neurodegenerative conditions such as primary progressive aphasia or mild cognitive impairment. The investigators seek to expand on this literature by investigating how anodal tDCS paired with and without cognitive training will impact executive functioning in PPA with Frontotemporal Dementia or Alzheimer's Disease pathology and Mild Cognitive Impairment/Alzheimer's Disease (e.g. shifting, updating, monitoring, and manipulation).
Interventions
- OTHER Computerized Cognitive Training
- DEVICE Active tDCS (tDCS) on DLPFC
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2023-08-10 |
| Est. Completion | 2025-09-10 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05978804
The ClinicalTrials.gov registry entry for NCT05978804 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Computerized Cognitive Training is the first listed.
NCT05978804 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05978804 about?
NCT05978804 is a clinical study titled "Home-based tDCS in Frontotemporal Dementia or Alzheimer's Disease". The primary objective of this research is to evaluate the effects of non-invasive brain stimulation and computerized cognitive training on executive functioning in individuals with Primary Progressive Aphasia (PPA), mild cognitive impairment (MCI), or dementia. In this study, investigators will use ...
What is the current status of trial NCT05978804?
This trial is currently terminated. It is a NA study. The enrollment target is 36 participants. The study started on 2023-08-10. Estimated completion is 2025-09-10.
What interventions are being tested in trial NCT05978804?
The interventions under investigation include: Computerized Cognitive Training (OTHER), Active tDCS (tDCS) on DLPFC (DEVICE).
Who is sponsoring clinical trial NCT05978804?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
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