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NCT05943210 · ClinicalTrials.gov registry record · NA

The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer

A NA study of Rectal Cancer, sponsored by Weill Medical College of Cornell University.

Recruiting
Registry status
NA
Development phase
25
Enrollment target
5
Study locations

NCT05943210: Recruiting NA study of Rectal Cancer, sponsored by Weill Medical College of Cornell University.

NCT05943210 is a NA study of Rectal Cancer that is actively recruiting participants, run by Weill Medical College of Cornell University. The registered enrollment target is 25 participants, below the 3,167-participant average among 70 other Rectal Cancer trials with a reported enrollment target (99% lower). The trial reports 5 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05943210, a NA study of Rectal Cancer, is actively recruiting participants, sponsored by Weill Medical College of Cornell University.

RECRUITING
Registry status
NA
Development phase
25 participants
Enrollment target
5
Study locations

Study Summary

This trial (molecular characterization trial) focuses on rectal cancer, a common cancer that is treated with radiotherapy (RT) as standard of care and represents a setting in which to study the effects of RT on the immune system.

Primary Outcome

To conduct a multi-centric prospective clinical trial of standard short course RT in the neoadjuvant setting of rectal cancer (MCT), with harmonized tissue acquisition and immune characterization across seven international centers, and assess quality of life during MCT and pathological response at surgery.

Conditions Studied

Interventions

  • RADIATION Short Course Radiation Therapy (scRT)
  • PROCEDURE Total Mesenteric Excision (TME)

Study Locations (5)

New York

  • New York Presbyterian Brooklyn Methodist Hospital - Brooklyn
  • Weill Cornell Medical College - New York
  • New York Presbyterian Hospital - Queens - New York

Illinois

  • The University of Chicago - Chicago

New Jersey

  • Rutgers Cancer Institute of New Jersey - New Brunswick

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2023-05-22
Est. Completion 2028-05-31
Phase NA

What NCT05943210 shows while recruiting

NCT05943210 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 3,167-participant average among 70 other Rectal Cancer trials with a reported enrollment target (99% lower).

The record links to 1 condition, with Rectal Cancer appearing as the primary indexed condition, and to 2 interventions - of which Short Course Radiation Therapy (scRT) is the first listed.

NCT05943210 lists 5 locations in 3 states (New York, Illinois, New Jersey).

Frequently Asked Questions

What is clinical trial NCT05943210 about?

NCT05943210 is a clinical study titled "The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer". This trial (molecular characterization trial) focuses on rectal cancer, a common cancer that is treated with radiotherapy (RT) as standard of care and represents a setting in which to study the effects of RT on the immune system.

What is the current status of trial NCT05943210?

This trial is currently recruiting. It is a NA study. The enrollment target is 25 participants. The study started on 2023-05-22. Estimated completion is 2028-05-31.

What conditions does trial NCT05943210 study?

This clinical trial studies the following conditions: Rectal Cancer.

What interventions are being tested in trial NCT05943210?

The interventions under investigation include: Short Course Radiation Therapy (scRT) (RADIATION), Total Mesenteric Excision (TME) (PROCEDURE).

Who is sponsoring clinical trial NCT05943210?

This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05943210 being conducted?

This trial has 5 study locations across Illinois, New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Rectal Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05943210's enrollment target sits among peer trials

25 57th of 70 higher than 13 of 70 other Rectal Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Rectal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05943210, the US trial registry maintained by the National Library of Medicine. NCT05943210 (small enrollment · multi site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.