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NCT05934305 · ClinicalTrials.gov registry record · NA

Mitigating the Impact of Stigma and Shame Among People Living With HIV and Substance Use Disorders

A NA study of HIV and Substance Use Disorders, sponsored by Boston University.

Recruiting
Registry status
NA
Development phase
256
Enrollment target
2
Study locations

NCT05934305 is a NA study of HIV and Substance Use Disorders that is actively recruiting participants, run by Boston University. The registered enrollment target is 256 participants, below the 439-participant average among 303 other HIV trials with a reported enrollment target (42% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT05934305, a NA study of HIV and Substance Use Disorders, is actively recruiting participants, sponsored by Boston University.

RECRUITING
Registry status
NA
Development phase
256 participants
Enrollment target
2
Study locations

Study Summary

People living with HIV and substance use disorders (SUDs) are less likely to be virally suppressed, which can lead to HIV transmission and negative health outcomes. This hybrid type 1 study will assess the efficacy, mechanisms, as well as facilitators and barriers to implementing the MATTER intervention, a virtually delivered 5-session text-enhanced psychobehavioral intervention designed to facilitate viral suppression by addressing internalized stigma and shame as barriers to engagement in HIV care among individuals living with HIV and SUDs in two locations with different levels of HIV resources (i.e., the Boston, Massachusetts and Miami, Florida metro areas). MATTER aims to mitigate the negative behavioral consequences of internalized stigma and shame on viral suppression by a) developing behavioral self-care goal setting skills and related self-efficacy, b) increasing metacognitive awareness (i.e., non-judgmental awareness of emotions and cognitions), and c) teaching and reinforcing compassionate self-restructuring (i.e., self- compassion), in addition to providing access to phone-based resource navigation. Scalable interventions such as MATTER are essential to our efforts to end the HIV epidemic in high priority regions.

Conditions Studied

HIV Substance Use Disorders

Interventions

  • BEHAVIORAL Control Condition
  • BEHAVIORAL Matter Intervention

Study Locations (2)

Florida

  • Florida International University - Miami

Massachusetts

  • Fenway Health - Boston

Trial Details

FieldValue
Enrollment Target 256 participants
Start Date 2025-03-12
Est. Completion 2028-07
Phase NA

Sponsor

Boston University

185 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05934305

The ClinicalTrials.gov registry entry for NCT05934305 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 256 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 439-participant average among 303 other HIV trials with a reported enrollment target (42% lower). The listed sponsor is Boston University, which has 185 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with HIV appearing as the primary indexed condition, and to 2 interventions - of which Control Condition is the first listed.

NCT05934305 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Florida, Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05934305 about?

NCT05934305 is a clinical study titled "Mitigating the Impact of Stigma and Shame Among People Living With HIV and Substance Use Disorders". People living with HIV and substance use disorders (SUDs) are less likely to be virally suppressed, which can lead to HIV transmission and negative health outcomes. This hybrid type 1 study will assess the efficacy, mechanisms, as well as facilitators and barriers to implementing the MATTER interven...

What is the current status of trial NCT05934305?

This trial is currently recruiting. It is a NA study. The enrollment target is 256 participants. The study started on 2025-03-12. Estimated completion is 2028-07.

What conditions does trial NCT05934305 study?

This clinical trial studies the following conditions: HIV, Substance Use Disorders.

What interventions are being tested in trial NCT05934305?

The interventions under investigation include: Control Condition (BEHAVIORAL), Matter Intervention (BEHAVIORAL).

Who is sponsoring clinical trial NCT05934305?

This trial is sponsored by Boston University, which has 185 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05934305 being conducted?

This trial has 2 study locations across Florida, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.