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NCT05930821 · ClinicalTrials.gov registry record · NA
Exercise Training, Cognition, and Mobility in Older Adults With Multiple Sclerosis
A NA study of Multiple Sclerosis and Cognitive Impairment, sponsored by University of Illinois at Chicago.
- Active
- Registry status
- NA
- Development phase
- 51
- Enrollment target
- 1
- Study location
NCT05930821 is a NA study of Multiple Sclerosis and Cognitive Impairment that is active but no longer recruiting, run by University of Illinois at Chicago. The registered enrollment target is 51 participants, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05930821, a NA study of Multiple Sclerosis and Cognitive Impairment, is active but no longer recruiting, sponsored by University of Illinois at Chicago.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 51 participants
- Enrollment target
- 1
- Study location
Study Summary
The overall objective of the proposed randomized controlled (RCT) is to determine the feasibility and efficacy of a 16-week theory-based, remotely-delivered, combined exercise (aerobic and resistance) training intervention for improving cognitive and physical function in older adults (50+ years) with multiple sclerosis (MS) who have mild-to-moderate cognitive and walking impairment. Participants (N=50) will be randomly assigned into exercise training (combined aerobic and resistance exercise) condition or active control (flexibility and stretching) condition. The 16-week intervention will be delivered and monitored remotely within a participant's home/community and supported by Zoom-based chats guided by social cognitive theory (SCT) via a behavioral coach. Participants will receive training materials (e.g., prescriptive manual and exercise equipment), one-on-one coaching, action-planning via calendars, self-monitoring via logs, and SCT-based newsletters. It is hypothesized that the home-based exercise intervention will yield beneficial effects on cognition, mobility, physical activity, and vascular function compared with an active control condition (flexibility and stretching intervention), and these improvements will be sustained during a 16-week follow-up period.
Conditions Studied
Interventions
- BEHAVIORAL Aerobic and Resistance Exercise Program (GEMS program)
- BEHAVIORAL Flexibility and Stretching Program (FLEX-MS program)
Study Locations (1)
Illinois
- University of Illinois at Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 51 participants |
| Start Date | 2023-07-05 |
| Est. Completion | 2025-03-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05930821
The ClinicalTrials.gov registry entry for NCT05930821 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 51 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (91% lower). The listed sponsor is University of Illinois at Chicago, which has 430 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Multiple Sclerosis appearing as the primary indexed condition, and to 2 interventions - of which Aerobic and Resistance Exercise Program (GEMS program) is the first listed.
NCT05930821 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT05930821 about?
NCT05930821 is a clinical study titled "Exercise Training, Cognition, and Mobility in Older Adults With Multiple Sclerosis". The overall objective of the proposed randomized controlled (RCT) is to determine the feasibility and efficacy of a 16-week theory-based, remotely-delivered, combined exercise (aerobic and resistance) training intervention for improving cognitive and physical function in older adults (50+ years) wit...
What is the current status of trial NCT05930821?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 51 participants. The study started on 2023-07-05. Estimated completion is 2025-03-31.
What conditions does trial NCT05930821 study?
This clinical trial studies the following conditions: Multiple Sclerosis, Cognitive Impairment, Older Adults, Walking Impairment.
What interventions are being tested in trial NCT05930821?
The interventions under investigation include: Aerobic and Resistance Exercise Program (GEMS program) (BEHAVIORAL), Flexibility and Stretching Program (FLEX-MS program) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05930821?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05930821 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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