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NCT05929937 · ClinicalTrials.gov registry record · Phase 4
No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair
A Phase 4 study of Postoperative Pain and Inguinal Hernia, sponsored by Clayton Petro.
- Active
- Registry status
- Phase 4
- Development phase
- 904
- Enrollment target
- 8
- Study locations
NCT05929937: Active Phase 4 study of Postoperative Pain and Inguinal Hernia, sponsored by Clayton Petro.
NCT05929937 is a Phase 4 study of Postoperative Pain and Inguinal Hernia that is active but no longer recruiting, run by Clayton Petro. The registered enrollment target is 904 participants, above the 224-participant average among 120 other Postoperative Pain trials with a reported enrollment target (304% higher). The trial reports 8 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05929937, a Phase 4 study of Postoperative Pain and Inguinal Hernia, is active but no longer recruiting, sponsored by Clayton Petro.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 4
- Development phase
- 904 participants
- Enrollment target
- 8
- Study locations
Study Summary
The investigators hypothesize that not prescribing opioids after uncomplicated, outpatient IHR will be non-inferior to prescribing opioids (5 tablets of Oxycodone, 5mg; or surgeon preference for intolerance) with respect to requests for opioid refills. Additionally, the investigators believe there will be no significant difference in postoperative readmission for pain quality of life at 30 days in either group.
Primary Outcome
The number of opioid prescription refills/requests will be compared between the two groups
Conditions Studied
Interventions
- DRUG Opioids
- OTHER No opioids
Study Locations (8)
Ohio
- University Hospitals - Cleveland
- Cleveland Clinic Center for Abdominal Core Health - Cleveland
California
- MemorialCare - Fountain Valley
Michigan
- Corewell Health - Royal Oak
South Carolina
- Prisma Health - Greenville
Tennessee
- University of Tennessee Medical Center - Knoxville
Wisconsin
- Medical College of Wisconsin - Milwaukee
Ontario
- North York General Hospital - Toronto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 904 participants |
| Start Date | 2023-07-10 |
| Est. Completion | 2027-07 |
| Phase | Phase 4 |
What the registry record for NCT05929937 still lists
NCT05929937 is an interventional study that assigns participants to a tested intervention. The registered 904 participants enrollment target is mid-sized for trials with a published cap, above the 224-participant average among 120 other Postoperative Pain trials with a reported enrollment target (304% higher).
The record links to 2 conditions, with Postoperative Pain appearing as the primary indexed condition, and to 2 interventions - of which Opioids is the first listed.
NCT05929937 lists 8 locations in 7 states (Ohio, California, Michigan).
Frequently Asked Questions
What is clinical trial NCT05929937 about?
NCT05929937 is a clinical study titled "No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair". The investigators hypothesize that not prescribing opioids after uncomplicated, outpatient IHR will be non-inferior to prescribing opioids (5 tablets of Oxycodone, 5mg; or surgeon preference for intolerance) with respect to requests for opioid refills. Additionally, the investigators believe there w...
What is the current status of trial NCT05929937?
This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 904 participants. The study started on 2023-07-10. Estimated completion is 2027-07.
What conditions does trial NCT05929937 study?
This clinical trial studies the following conditions: Postoperative Pain, Inguinal Hernia.
What interventions are being tested in trial NCT05929937?
The interventions under investigation include: Opioids (DRUG), No opioids (OTHER).
Who is sponsoring clinical trial NCT05929937?
This trial is sponsored by Clayton Petro, which has 5 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05929937 being conducted?
This trial has 8 study locations across California, Michigan, Ohio, South Carolina, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05929937's enrollment target sits among peer trials
904 5th of 120 higher than 116 of 120 other Postoperative Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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