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NCT05925530 · ClinicalTrials.gov registry record · Phase 2
Study to Assess Neoadjuvant Durvalumab (D) and Platinum-Based Chemotherapy (CT), Followed by Either Surgery and Adjuvant D or CRT and Consolidation D, in Resectable or Borderline Resectable Stage IIB-IIIB NSCLC (MDT-BRIDGE)
A Phase 2 study of Non-Small Cell Lung Cancer, sponsored by AstraZeneca.
- Active
- Registry status
- Phase 2
- Development phase
- 142
- Enrollment target
- 20
- Study locations
NCT05925530 is a Phase 2 study of Non-Small Cell Lung Cancer that is active but no longer recruiting, run by AstraZeneca. The registered enrollment target is 142 participants, below the 659-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (78% lower). The trial reports 20 study locations across 6 states.
The verdict
NCT05925530, a Phase 2 study of Non-Small Cell Lung Cancer, is active but no longer recruiting, sponsored by AstraZeneca.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 142 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to assess efficacy and safety of neoadjuvant durvalumab in combination with platinum-based chemotherapy (CT) given as initial therapy after cancer diagnosis followed by either surgery and adjuvant durvalumab or chemoradiotherapy (CRT) and consolidation durvalumab given alone as further therapy in participants with resectable and borderline resectable stage IIB-IIIB NSCLC.
Conditions Studied
Interventions
- DRUG Durvalumab
Study Locations (20)
Other
- Research Site - Vienna
- Research Site - Vienna
- Research Site - Brno
- Research Site - Olomouc
- Research Site - Prague
- Research Site - Prague
- Research Site - La Tronche
- Research Site - Marseille
- Research Site - Montpellier
- Research Site - Mulhouse
- Research Site - Paris
- Research Site - Pessac
- Research Site - Poitiers
- Research Site - Toulouse
Quebec
- Research Site - Chicoutimi
- Research Site - Montreal
New York
- Research Site - The Bronx
Texas
- Research Site - Houston
Virginia
- Research Site - Charlottesville
Ontario
- Research Site - Kingston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 142 participants |
| Start Date | 2024-02-22 |
| Est. Completion | 2027-08-27 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05925530
The ClinicalTrials.gov registry entry for NCT05925530 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 142 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 659-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (78% lower). The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Non-Small Cell Lung Cancer appearing as the primary indexed condition, and to 1 intervention - of which Durvalumab is the first listed.
NCT05925530 reports 20 study locations spanning 6 distinct geographic areas - top geographies include Other, Quebec, New York.
Frequently Asked Questions
What is clinical trial NCT05925530 about?
NCT05925530 is a clinical study titled "Study to Assess Neoadjuvant Durvalumab (D) and Platinum-Based Chemotherapy (CT), Followed by Either Surgery and Adjuvant D or CRT and Consolidation D, in Resectable or Borderline Resectable Stage IIB-IIIB NSCLC (MDT-BRIDGE)". The purpose of this study is to assess efficacy and safety of neoadjuvant durvalumab in combination with platinum-based chemotherapy (CT) given as initial therapy after cancer diagnosis followed by either surgery and adjuvant durvalumab or chemoradiotherapy (CRT) and consolidation durvalumab given a...
What is the current status of trial NCT05925530?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 142 participants. The study started on 2024-02-22. Estimated completion is 2027-08-27.
What conditions does trial NCT05925530 study?
This clinical trial studies the following conditions: Non-Small Cell Lung Cancer.
What interventions are being tested in trial NCT05925530?
The interventions under investigation include: Durvalumab (DRUG).
Who is sponsoring clinical trial NCT05925530?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05925530 being conducted?
This trial has 20 study locations across New York, Texas, Virginia, Ontario, Quebec. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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